Results 201 to 210 of about 3,115,715 (297)

Quantifying transcript complexity via the condition number of gene-specific random matrix. [PDF]

Brief Bioinform
Zhang B, Guo Y, Liu G, Zou M.
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

IL-8-driven neutrophil NETosis triggers endothelial apoptosis and exacerbates preeclampsia. [PDF]

J Transl Med
Li W, Li X, Liu X, Zhang M, Li W, Jiao X, Gao F, Cui B.   +7 more
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Harmonizing HIV-1 RNA laboratory measurements in a longitudinal cohort collaboration. [PDF]

Am J Epidemiol
Lee JS, Humes E, Haw NJL, Hogan B, Zheng C, Coburn S, Lesko CR, Lang R, Gill MJ, Horberg M, Silverberg MJ, Palella FJ, Delaney JA, Rebeiro PF, Sterling T, Rodriguez-Barradas M, Marconi VC, Yendewa GA, Klein MB, Moore R, Althoff KN, Research And Design Na-Accord OBOTNAACCO.   +21 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Accurate quantification of the bacterial inoculum and tissue load in a preclinical model of implant-related infection. [PDF]

Bone Joint Res
Sun Q, Muratovic D, Anderson PH, Sawyer R, Tsangari H, Solomon LB, Atkins GJ, Yang D.   +7 more
europepmc   +1 more source

Quantificational logic

Information and Control, 1960
openaire   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Tumor-derived DNA drives cancer-associated anemia by promoting reticulocyte clearance. [PDF]

Signal Transduct Target Ther
Yuan T, Liu X, Wu Y, Li S, Chu H, Li Q, Chen Z, Liu H, Mao T, Zha H, Cheng X, Jing J, Li C, Peng L, Chen X, Liao Q, Yu R, Lv H, Zhang J, Wang Z, Jia Q, Long H, Chen D, Zhu B.   +23 more
europepmc   +1 more source