Results 81 to 90 of about 129,657 (289)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
On quantifier raising in German [PDF]
, 2009 The status of quantifier raising in German and other languages where scope is fairly rigid is debated. The first part of this paper argues that quantifiers in German can undergo covert extraction out of coordinations, and therefore that quantifier ...
Sauerland, Uli
core
Informal Logic, 1991 This article explores a mapping of the formal probability calculus onto the informal logic concepts of acceptability and sufficiency, concluding that while this approach is technically feasible, its value for understanding real-life arguments is limited. This article was originally published as: Black, J. (1991). Quantifying support. Informal Logic, 13(
openaire +5 more sources
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Quantifying quantifier representations
, 2022 This thesis presents experimental and computational modeling studies on the mental representations of the natural language quantifiers (e.g., most, many, few, more than half, and fewer than half). According to the dominant logical approach in cognitive semantics, the meaning of quantifiers can be expressed in the form of truth conditions.
openaire +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Characterising Context-Independent Quantifiers and Inferences
Studia HumanaContext is essential in virtually all human activities. Yet some logical notions seem to be context-free. For example, the nature of the universal quantifier, the very meaning of “all”, seems to be independent of the context.
Krajewski Stanisław
doaj +1 more source
Bare quantifier fronting as contrastive topicalization [PDF]
Bucharest Working Papers in Linguistics, 2015 I argue that indefinites (in particular bare quantifiers such as ‘something’, ‘somebody’, etc.) which are neither existentially presupposed nor in the restriction of a quantifier over situations, can undergo topicalization in a number of Romance ...
Ion Giurgea
doaj
Implicit Assessment and Argumentation
Научный диалог, 2020 The article is devoted to the problem of implicitness. As an object of study, sentences with a conjunction but, sentences with a conjunction and , sentences with a quantifier word any (a quantifier of generality) and sentences with a construction of the ...
E. R. Ioanesyan
doaj +1 more source