Results 221 to 230 of about 354,417 (335)
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Lexicogrammatical profiling of ASD: cognitive-functional mapping and diagnostic implications. [PDF]
Kato S, Hanawa K.
europepmc +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Quantifier processing and semantic flexibility in patients with aphasia. [PDF]
Reißner B +6 more
europepmc +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Most quantifiers have many meanings. [PDF]
Ramotowska S +3 more
europepmc +1 more source
Summary: Symmetry is all pervasive -- from the day/night cycle to the rise and fall of the tides, from geometry to physics. It is thus natural that mathematicians should want to study symmetry, to quantify it, to exploit it. At its core, this article is about quantifying the amount of symmetry in an object and separating those that, in a certain well ...
openaire +1 more source

