Results 101 to 110 of about 73,349 (260)

Integrative Omics Analysis Reveals the Regulation of Hypoxia Tolerance in Large Yellow Croaker (Larimichthys crocea) via the Lipoic Acid Synthase (lias) Gene

open access: yesAdvanced Science, EarlyView.
Lipoic acid synthase (lias) can regulate α‐KG levels through lipoylation, thereby negatively regulating HIF‐1α protein levels via PHD under hypoixa. The Hap2 allele of lias exhibits lower expression levels than Hap1, leading to the accumulation of more HIF‐1α protein and thereby enhancing hypoxia tolerance. ABSTRACT Hypoxia stress seriously affects the
Jie Ding   +7 more
wiley   +1 more source

Whole‐Genome Sequencing Pilot of the Central Asian Genomic Diversity Project Reveals Distinct Histories, Adaptation, and Introgression

open access: yesAdvanced Science, EarlyView.
As a pilot phase of the Central Asian Genomic Diversity Project, whole‐genome sequencing of 166 individuals from 20 Central Asian and Afghan Hazara populations reveals fine‐scale substructure shaped by repeated trans‐Eurasian migration and admixture. Integrated analyses uncover post‐admixture adaptation, archaic introgression, and medically relevant ...
Mengge Wang   +11 more
wiley   +1 more source

Harnessing Large‐Scale Multi‐Omics Data for Risk Prediction and Deep Phenotyping of Valvular Heart Diseases in the General Population

open access: yesAdvanced Science, EarlyView.
Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang   +10 more
wiley   +1 more source

Model‐Based Bayesian Optimization for Organic Photovoltaics: Combining Bayesian Optimization With Physical Domain Knowledge

open access: yesAdvanced Energy Materials, EarlyView.
Integration of a physical solar cell model into Bayesian optimization is performed using the Knowledge Gradient acquisition function to balance exploration and exploitation. Experimental validation on the PTQ10:BTP‐eC9 material system and statistical validation on an OPV benchmark function show that the model‐based approach outperforms conventional ...
Leonard Christen, Thomas Kirchartz
wiley   +1 more source

Quantile Function on Scalar Regression Analysis for Distributional Data. [PDF]

open access: yesJ Am Stat Assoc, 2020
Yang H   +3 more
europepmc   +1 more source

Adapting to Changing Rainfall and Developing Off‐Farm Employment: Implications for the Adoption of Direct Seeding in Rice Production

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT Rice is the main staple food for more than half of the world's population and the income from rice is an essential source for livelihoods of millions of households. We examine whether direct seed in rice production is an adaptation of rice farmers to rainfall changes and farm labor scarcity.
Manh Hung Do
wiley   +1 more source

The Unit Arcsine–Exponential Distribution and Its Statistical Properties with Inference and Application to Reliability Data

open access: yesAxioms
This paper presents a new continuous data model, the Unit Arcsine–Exponential distribution (UASED), a flexible data model on the unit interval. It is built up by an exponential-based arcsine-type transformation to allow it to represent a very wide range ...
Asmaa S. Al-Moisheer   +3 more
doaj   +1 more source

Alternative Means of Statistical Data Analysis: L-Moments and TL-Moments of Probability Distributions [PDF]

open access: yesStatistika: Statistics and Economy Journal, 2014
Moments and cumulants are commonly used to characterize the probability distribution or observed data set. The use of the moment method of parameter estimation is also common in the construction of an appropriate parametric distribution for a certain ...
Diana Bílková
doaj  

Coping With Production Risk: Effects of Sown Plant Diversity on the Attractiveness of Crop Insurance in Grasslands

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT Increased frequency of extreme weather events, particularly droughts, threatens grassland farming by destabilizing yields and farms' economic viability. We examine, theoretically and through numerical simulations, how sown plant diversity (natural insurance) influences the attractiveness of indemnity and drought index insurance (formal ...
Nicolas Alou   +3 more
wiley   +1 more source

Statistical Analysis of the Induced Ailamujia Lifetime Distribution with Engineering and Bidomedical Applications

open access: yesMathematics
Accurate modeling of industrial and biomedical data is often challenging due to skewness, heavy tails, and complex variability, which traditional probability distributions fail to capture.
Mahmoud M. Abdelwahab   +4 more
doaj   +1 more source

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