Results 41 to 50 of about 73,349 (260)

Optimal subsampling for functional quantile regression

open access: yesStatistical Papers, 2022
Subsampling is an efficient method to deal with massive data. In this paper, we investigate the optimal subsampling for linear quantile regression when the covariates are functions. The asymptotic distribution of the subsampling estimator is first derived.
Qian Yan, Hanyu Li, Chengmei Niu
openaire   +3 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

New Odd Generalized Exponentiated Exponential-G Family of Distributions

open access: yesUMYU Scientifica Journal, 2023
In the last decades, many researchers have developed new methods for generating families of distributions. These generators are obtained by adding one or more extra shape parameter(s) to the baseline distribution to achieve more flexibility for ...
Abideen Babatunde Odeyale   +3 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Uncertainty orders on the sublinear expectation space

open access: yesOpen Mathematics, 2016
In this paper, we introduce some definitions of uncertainty orders for random vectors in a sublinear expectation space. We all know that, under some continuity conditions, each sublinear expectation 𝔼 has a robust representation as the supremum of a ...
Tian Dejian, Jiang Long
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Mycophenolate Mofetil Treatment Reduces the Risk of Treatment Escalation Due to Vascular Complications in Limited Cutaneous Systemic Sclerosis: Emulation of a Target Trial From the Italian Rheumatology Society SPRING Registry

open access: yesArthritis Care &Research, EarlyView.
Objective Mycophenolate mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon because of the lower fibrotic burden and the predominance of vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis   +77 more
wiley   +1 more source

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

open access: yesAdvanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt   +8 more
wiley   +1 more source

Bivariate Quantile Functions and their Applications to Reliability Modelling

open access: yesStatistica, 2019
In this paper we propose a new definition of bivariate quantile function suited for reliability modelling and illustrate its applications. The bivariate hazard and mean residual quantile functions are defined and their properties are studied. Examples of
Balakrishnapillai Vineshkumar   +1 more
doaj   +1 more source

A Quantile Functions-Based Investigation on the Characteristics of Southern African Solar Irradiation Data

open access: yesMathematical and Computational Applications, 2023
Exploration of solar irradiance can greatly assist in understanding how renewable energy can be better harnessed. It helps in establishing the solar irradiance climate in a particular region for effective and efficient harvesting of solar energy ...
Daniel Maposa   +2 more
doaj   +1 more source

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