Results 71 to 80 of about 1,350 (213)

Natural Variation of COLD and CATECHINS REGULATOR 1 Coordinately Fine‐Tunes Cold Tolerance and Tea Quality in Tea Plants

open access: yesAdvanced Science, EarlyView.
Multi‐trait genome‐wide association mapping identifies a central hub regulator, COLD AND CATECHINS REGULATOR 1 (CCR1), and its excellent natural allele variation, coordinately enhancing cold tolerance and promoting catechins biosyntheis. CsCCR1 interacts with CsCBF1/3 and is transcriptionally activated by CsLUX and CsKUA1 to promote catechins ...
Yanli Wang   +10 more
wiley   +1 more source

Penalized function-on-function linear quantile regression

open access: yesComputational Statistics
We introduce a novel function-on-function linear quantile regression model to characterize the entire conditional distribution of a functional response for a given functional predictor. Tensor cubic $B$-splines expansion is used to represent the regression parameter functions, where a derivative-free optimization algorithm is used to obtain the ...
Ufuk Beyaztas   +2 more
openaire   +2 more sources

Integrative Omics Analysis Reveals the Regulation of Hypoxia Tolerance in Large Yellow Croaker (Larimichthys crocea) via the Lipoic Acid Synthase (lias) Gene

open access: yesAdvanced Science, EarlyView.
Lipoic acid synthase (lias) can regulate α‐KG levels through lipoylation, thereby negatively regulating HIF‐1α protein levels via PHD under hypoixa. The Hap2 allele of lias exhibits lower expression levels than Hap1, leading to the accumulation of more HIF‐1α protein and thereby enhancing hypoxia tolerance. ABSTRACT Hypoxia stress seriously affects the
Jie Ding   +7 more
wiley   +1 more source

Nonparametric Estimation of Quantile-Based Mean Inactivity Time Function

open access: yesStatistica
In this article, we propose non-parametric estimators for mean inactivity time function for complete and censored data. The asymptotic properties of the estimators are established using suitable regularity conditions.
Ivallappil Chenichery Aswin   +2 more
doaj   +1 more source

Whole‐Genome Sequencing Pilot of the Central Asian Genomic Diversity Project Reveals Distinct Histories, Adaptation, and Introgression

open access: yesAdvanced Science, EarlyView.
As a pilot phase of the Central Asian Genomic Diversity Project, whole‐genome sequencing of 166 individuals from 20 Central Asian and Afghan Hazara populations reveals fine‐scale substructure shaped by repeated trans‐Eurasian migration and admixture. Integrated analyses uncover post‐admixture adaptation, archaic introgression, and medically relevant ...
Mengge Wang   +11 more
wiley   +1 more source

Posterior Probabilities of Dominance for Wealth Distributions

open access: yesEconometrics
Probability distributions, which are typically used to describe income distributions, are not suitable to describe a population’s distribution of wealth because of the existence of negative observations and a large concentration of values close to zero ...
William Griffiths   +1 more
doaj   +1 more source

The Log-Expo Inverse Gompertz Distribution: properties and Estimations [PDF]

open access: yesMaǧallaẗ Al-Buḥūṯ Al-Mālīyyaẗ wa Al-Tiğāriyyaẗ
This paper introduces the Log-Expo Inverse Gompertz Distribution (LET-IG) three-parameter distribution and examines some of its mathematical properties. The study derives the density distribution, reliability function, and hazard rate function.
محمد عبد القادر   +1 more
doaj   +1 more source

Harnessing Large‐Scale Multi‐Omics Data for Risk Prediction and Deep Phenotyping of Valvular Heart Diseases in the General Population

open access: yesAdvanced Science, EarlyView.
Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang   +10 more
wiley   +1 more source

Risk of Inflammatory Bowel Disease Following Hospital‐Treated Infections and Modulatory Role of Host Genetics to Support a Multi‐Hit Pathogenesis Model

open access: yesAdvanced Science, EarlyView.
Hospital‐treated infections are linked to increased risk of inflammatory bowel disease in a large prospective cohort. This risk differs by infection burden, time since infection, and host immune‐genetic susceptibility. The findings support a multi‐hit pathogenesis model in which severe infection and inherited susceptibility jointly shape inflammatory ...
Haiming Zhuang   +16 more
wiley   +1 more source

Recovery of a quantile function from moments

open access: yesJournal of Computational and Applied Mathematics, 2017
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Robert M. Mnatsakanov   +1 more
openaire   +1 more source

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