Results 221 to 230 of about 3,710,099 (267)

Impact of process parameters on IgG glycosylation in CHO systems: a comprehensive quantitative analysis. [PDF]

MAbs
Bravo-Venegas J, Rodriguez-Siza J, Vergara M, Torres M, Dickson A, Toledo JR, Molina MC, Hermoso MA, Berríos J, Altamirano C.   +9 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Automated quantitative analysis of osteoclast numbers and areas in cell culture plates using the YOLOv8 instance segmentation model. [PDF]

MethodsX
Huang J, Li Z, Ouyang J, Li J, Fan Y, Huang D, Dong M, Jin F, Lu Y.   +8 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Quantitative analysis of gaze and body movement differences by proficiency in direct and video laryngoscope intubation. [PDF]

Sci Rep
Yasuda Y, Takehara S, Inoue S.
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Cadmium inhibits hSMUG1-mediated uracil excision: quantitative analysis and mitigation by <i>Ganoderma lucidum</i> extracts. [PDF]

J Enzyme Inhib Med Chem
Chang HL, Fang CH, Chang HL, Lee YF, Hsu WL, Chang JH, Chien MH, Goodman SD, Chang SY, Fang WH, Su KY.   +10 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Carapics: A Web-based Platform for Semi-quantitative Analysis of Structural Change in Biological Samples. [PDF]

MicroPubl Biol
Dickinson GH, Yoon S, Sorvino N, Kamal S, Hoppe CJ, Ahmad I, Long WC.   +6 more
europepmc   +1 more source