Results 171 to 180 of about 1,175,148 (341)

Special Issue on Women in Proteomics. [PDF]

Mol Cell Proteomics
Huang L, Gavin AC, Choudhary JS.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Development of Mass Spectrometry Molecular Analysis Strategies and Chemistries for the Quantitative Measurement of Glycans in Complex Biological Systems.

, 2017
Elizabeth S. Hecht
openalex   +1 more source

Science Process Skills Acquired by Senior Secondary School Chemistry Students in Quantitative Analysis in Enugu Education Zone, Nigeria [PDF]

, 2019
Florence Obiageli Ezeudu, Anselem Abonyi Ugwuanyi, Ameh Rachael Folake   +2 more
openalex   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Photoclick chemistry led to the identification of HELLS as a helicase for DNA G-quadruplexes. [PDF]

Nucleic Acids Res
Gao Z, Chong Y, He X, Yuan J, Wang Y.
europepmc   +1 more source

Development of Quantitative Standards for Atom Probe Reconstruction Parameters for Analysis of Interfacial Chemistry [PDF]

, 2015
Scott Broderick, Santoshrupa Dumpala, S. E. Young, Kaustubh Kaluskar, Srikant Srinivasan, Krishna Rajan   +5 more
openalex   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Synthesis and separation of two stereoisomers of deuterated tetrasubstituted allylic alcohols <i>via</i> consecutive dual 1,2-metallate shifts. [PDF]

Chem Sci
Li P, Yu Y, Ma X, Song Q.
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source