Results 81 to 90 of about 1,175,148 (341)

From lipid analysis to lipidomics

Тонкие химические технологии, 2012
This review provides information on the existing methods of lipid analysis. We describe the methods of extraction, separation and quantitative analysis of lipids, which include both well-known techniques and recent advances in analytical chemistry of ...
V. A. Akmurzina, A. A. Selishcheva, V. I. Shvets   +2 more
doaj  

Vaccination-Route-Dependent Adjuvanticity of Antigen-Carrying Nanoparticles for Enhanced Vaccine Efficacy

Vaccines
Vaccination-route-dependent adjuvanticity was identified as being associated with the specific features of antigen-carrying nanoparticles (NPs) in the present work.
Chaojun Song, Jinwei Hu, Yutao Liu, Yi Tian, Yupu Zhu, Jiayue Xi, Minxuan Cui, Xiaolei Wang, Bao-Zhong Zhang, Li Fan, Quan Li   +10 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

SPECIAL ASPECTS OF ANALYTICAL CHEMISTRY COURSE CONTENT OF WOULD-BE CHEMISTRY TEACHERS TRAINING IN PEDAGOGICAL UNIVERSITY

Вестник Самарского государственного технического университета. Серия: Психолого-педагогические науки, 2015
Analytical chemistry as an academic subject plays a significant role in would-be chemistry teachers training and alongside other disciplines it gives the students a solid foundation in their professional education.
Natalia V. Sukhankina
doaj  

Canonical Correlation Analysis for Understanding Foundational-Advanced Chemistry Classes Relationship and Their Role in Preparing Preservice Teacher

Indonesian Journal on Learning and Advanced Education (IJOLAE)
Mental models and the strength of basic chemistry concepts are the primary foundation for students to avoid obstacles in highly complex material. On the other hand, students' understanding of basic chemistry concepts has not been optimally developed ...
Almubarak Almubarak, Restu Prayogi, Sukmawati Yasim, Aidil Adhani   +3 more
doaj   +1 more source

The Knoevenagel reaction: a review of the unfinished treasure map to forming carbon–carbon bonds

Green Chemistry Letters and Reviews, 2020
The formation of carbon–carbon bonds is a quest that has required a lot of research throughout the last 125 years of history of chemistry. The creation of these bonds is key to producing a wide variety of advanced products with great societal importance.
Koen van Beurden, Steffijn de Koning, Dennis Molendijk, Jack van Schijndel   +3 more
doaj   +1 more source

FLow-injection analysis: a new approach to quantitative measurements in clinical chemistry.

Clinical Chemistry, 1982
Abstract Flow-injection analysis, founded on an approach that is entirely different from continuous-flow analysis, involves use of three principles: sample "injection," controlled dispersion of sample (rather than a dispersion retarded with gas bubbles), and reproducible timing.
B, Rocks, C, Riley
openaire   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Investigating The Impact of Acquired Fundamental Laboratory Skills in Chemistry on The Student's Actual Academic Achievement in Rutsiro District of Rwanda

SEAQIS Journal of Science Education
The enhancement of fundamental laboratory abilities in advanced learners has multiple implications for academic performance. Corrective action is necessary for secondary school pupils who are taking chemistry as a core subject because of their poor ...
Elie IZERE
doaj   +1 more source