Results 101 to 110 of about 55,393 (201)

Epilepsy-Induced Neurodegeneration and Its Therapeutic Interventions. [PDF]

Cureus
Kaddoura S, Banerjee A, Ganti L.
europepmc   +1 more source

Amodiaquine Enhances Anti‐Melanoma Efficacy of Attenuated Salmonella via Targeting Glutathione Reductase in Neutrophils

Advanced Science, EarlyView.
This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong, Chunyuan Zhao, Chengxi Li, Lin Weng, Zehan Ji, Peiqi Li, Jiqiang Lu, Danni Liu, Anni Yu, Tianyi Jiang, Shaokai Huang, Heng Liu, Xiao Chen, Zichun Hua   +13 more
wiley   +1 more source

Neural mechanisms of the V2M-PrL pathway mediate blue light-induced spatial memory impairment. [PDF]

Commun Biol
Zhang Y, Tong G, Wang W, Xu Y, Zhang W, Chen X, Wang X, Xu Q, Han C, Wang L, Weng S, Zhang P.   +11 more
europepmc   +1 more source

Broadband All‐Optical Memtransistor Based on Organic Cocrystals for Noise‐Robust Motion Recognition

Advanced Science, EarlyView.
This work presents an all‐optical synaptic transistor using DTT‐TCNQ organic charge transfer cocrystals, achieving broadband bidirectional modulation (395–808 nm) with highly linear synaptic plasticity (nonlinearity coefficients αp = 0.00191, αd = 0.00305).
Zhaohui Cai, Yuxiao Fang, Wenjie Du, Zhengjun Liu, Yingli Shi, Jiahua Luo, Rui Wu, Lixing Kang, Chun Zhao   +8 more
wiley   +1 more source

Quantum-like representation of neuronal networks' activity: modeling "mental entanglement". [PDF]

Front Hum Neurosci
Khrennikov A, Yamada M.
europepmc   +1 more source

A Closed‐Loop Hybrid Discovery System of Type I Photosensitizers for Hypoxic Tumor Therapy

Advanced Science, EarlyView.
The work developed a closed‐loop hybrid discovery system to rationally design and predict high‐performance Type I PSs for hypoxic tumor therapy. 664 Potential candidates are identified from a dataset through a support vector machine (SVM) classification model, and two candidates are experimentally verified as Type I PSs, which highlighted the potential
Xia Ling, Yixin Zhu, Min Li, Zongliang Xie, Lei Cao, Wentao Song, Dandan Wang, Duo Mao, Xiaonan Wang, Bin Liu   +9 more
wiley   +1 more source

The first 25 years of the Northwestern University SuperAging Program. [PDF]

Alzheimers Dement
Weintraub S, Gefen T, Geula C, Mesulam MM.   +3 more
europepmc   +1 more source

The Microbiota Shapes Central Nervous System Myelination in Early Life

Advanced Science, EarlyView.
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch, Emily G. Knox, Daniel Soong, Thomaz F. S. Bastiaanssen, Kalevi Trontti, Gabriel S. S. Tofani, Sophia Ivaschuk, Michael K. Collins, Donia Arafa, Jatin Nagpal, Iiris Hovatta, David A. Lyons, Gerard Clarke, John F. Cryan   +13 more
wiley   +1 more source

Higher-level spatial prediction in natural vision across mouse visual cortex. [PDF]

PLoS Comput Biol
Heilbron M, de Lange FP.
europepmc   +1 more source

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

Advanced Science, EarlyView.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen, Xin Wang, Haifeng Ding, Bosheng Zheng, Keni Zeng, Chuying Hu, Jiayi Liu, Xiao Zhu, Haibing Yu   +8 more
wiley   +1 more source