Results 181 to 190 of about 12,268 (219)

Impact of zervimesine on the neuroinflammatory biomarker GFAP and related proteomic molecular correlates in plasma of participants from a phase 2 clinical trial in Alzheimer's disease. [PDF]

Alzheimers Res Ther
Di Caro V, Cho E, Thiel J, Lizama BN, Koel-Simmelink MJA, Pandey K, Duong D, Seyfried NT, Grundman M, Teunissen CE, Zetterberg H, Blennow K, Caggiano AO, Hamby ME.   +13 more
europepmc   +1 more source

DeepMapper: Attention‐Based AutoEncoder for System Identification in Wound Healing and Stage Prediction

Advanced Intelligent Discovery, EarlyView.
The authors develop a deep learning model for real‐time tracking of wound progression. The deep learning framework maps the nonlinear evolution of a time series of images to a latent space, where they learn a linear representation of the dynamics. The linear model is interpretable and suitable for applications in feedback control.
Fan Lu, Ksenia Zlobina, Michael Briden, Oscar Avalos, Héctor Carrión, Sebastian Osorio, Hsin‐ya Yang, Alexandra Nava, Michelle D. Bagood, Marco Rolandi, Roslyn Rivkah Isseroff, Marcella Gomez   +11 more
wiley   +1 more source

Vimentin's Journey from "Background Scaffold" to Multi-Scale Regulator of Neuronal Growth and Function: Historical, Conceptual and Epistemic Perspectives. [PDF]

Int J Mol Sci
Gebreselase BA, Minin AA.
europepmc   +1 more source

Toward Intelligent Multimodal Holography for Real‐Time Chemical Imaging of Dynamic Ion Separation

Advanced Intelligent Discovery, EarlyView.
Intelligent multimodal holography integrates digital off‐axis holography, spectroscopic imaging, and AI‐driven reconstruction to visualize ion transport and chemical dynamics in real time. In this perspective paper, we outline how this approach enables label‐free, chemically specific monitoring of complex environments and discuss its potential to ...
Giovanna Ricchiuti, Sarah I. Allec, Maxim Ziatdinov, Venkateshkumar Prabhakaran   +3 more
wiley   +1 more source

Preoperative <i>APOE</i> and Alzheimer's disease polygenic risk profiling for perioperative neurocognitive disorders. [PDF]

Front Bioinform
Tan M, Zeng J, Zhou H, Yang S, Wang T, Zhong M, Wang T, Liu Z, Dai Y, Song S.   +9 more
europepmc   +1 more source

Autonomous AI‐Driven Design for Skin Product Formulations

Advanced Intelligent Discovery, EarlyView.
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang, Yongrui Xiao, Chunlin Chen, Dimitrios Tsaoulidis, Kai Yang, Tao Chen   +5 more
wiley   +1 more source

Editorial: What makes us human: from genes to machine. [PDF]

Front Neurosci
Segev I.
europepmc   +1 more source

Automated Bacterial Identification and Morphological Feature Analysis in Low‐Dose Cryo‐EM Using YOLOv11

Advanced Intelligent Discovery, EarlyView.
AI‐based tools enable rapid characterization of bacterial ultrastructure in low‐dose cryogenic transmission electron microscopy. The envelope thickness tool quantifies membrane thickness and anisotropy. The flagella module analyzes filament morphology and detects cell‐flagella contacts.
Sita Sirisha Madugula, Lynnicia N. Massenburg, Spenser R. Brown, Amber N. Bible, Chanda R. Harris, Lance X. Zhang, Kiara Parker, Scott T. Retterer, Jennifer L. Morrell‐Falvey, Rama K. Vasudevan, Alexis N. Williams   +10 more
wiley   +1 more source

Sex-dependent serotonergic signaling across development: molecular mechanisms shaping vulnerability to neurodevelopmental and mental disorders. [PDF]

Front Pharmacol
Palacios-Avendaño N, Rojas PS, Alarcón-Mardones M, Fiedler JL.   +3 more
europepmc   +1 more source

Parametric Analysis of Spiking Neurons in 16 nm Fin Field‐Effect Transistor Technology

Advanced Intelligent Discovery, EarlyView.
Energy efficient computing has driven a shift toward brain‐inspired neuromorphic hardware. This study explores the design of three distinct silicon neuron topologies implemented in 16 nm fin field‐Effect transistor technology. While the Axon‐Hillock design achieves gigahertz throughput, its functional fragility persists. The Morris–Lecar model captures
Logan Larsh, Raiyan Siddique, Sarah S. Sharif, Yaser Mike Banad   +3 more
wiley   +1 more source