Effect of Nanoparticle Rigidity on the Interaction of Stromal Membrane Particles with Leukemia Cells
Cell membrane nanoparticles made with stromal cells are prepared and used to target leukemia cells. Deposition of the cell membrane onto rigid silica cores leads to increased uptake both in leukemia cell lines and primary cells from patients. These results show that nanoparticle rigidity affects the interaction between cell membrane nanoparticles and ...
Sander de Weerd+8 more
wiley +1 more source
Shared Selection and Genetic Architecture Drive Strikingly Repeatable Evolution in Long-Term Experimental Hybrid Populations. [PDF]
Owens GL+5 more
europepmc +1 more source
Progress of Immune‐Inducible Biomaterials for Post‐Ablation Cancers
The presence of residual tumors after ablative therapies poses a significant challenge, generally resulting in recurrence and metastases. This review offers a concise overview of immune‐inducible biomaterials from the perspective of the cancer‐immunity cycle, and how they enhance antitumor immunity through diverse mechanisms following ablative ...
Shuangshuang Zhao+7 more
wiley +1 more source
Pleiotropy increases parallel selection signatures during adaptation from standing genetic variation. [PDF]
Lai WY+3 more
europepmc +1 more source
Si Inhibited Osteoclastogenesis: The Role of Fe and the Fenton Reaction
Silicate (Si) inhibition of osteoclastogenesis, is mediated by Fe. Si chemical interactions with Fe inhibit the Fenton reaction and intercellular ROS availability. This reduction in ROS availability inhibits osteoclastogenesis. The addition of Fe, in Si‐inhibited osteoclast cultures, restores the Fenton reaction, and osteoclastogenesis.
Yutong Li+7 more
wiley +1 more source
Precise lineage tracking using molecular barcodes demonstrates fitness trade-offs for ivermectin resistance in nematodes. [PDF]
Stevenson ZC+4 more
europepmc +1 more source
A novel one‐shot integration electropolymerization (OSIEP) method is developed as a breakthrough on the intricate photolithographic steps, enabling to compress all processes from synthesis to channel integration in one‐shot manufacturing. The specially designed dual bipolar electrodes provide the targeted depositions of poly(3,4‐ethylenedioxythiophene)
Jiyun Lee+9 more
wiley +1 more source
Plastic responses to past environments shape adaptation to novel selection pressures. [PDF]
Coates SER+7 more
europepmc +1 more source
Computational Simulations of Metal–Organic Frameworks to Enhance Adsorption Applications
This review highlights the significance of molecular simulations in expanding the understanding of metal–organic frameworks (MOFs) and improving their gas adsorption applications. The historical development and implementation of molecular simulations in the MOF field are given, high‐throughput computational screening studies used to unlock the ...
Hilal Daglar+3 more
wiley +1 more source
Recombinant inbred line panels inform the genetic architecture and interactions of adaptive traits in Drosophila melanogaster. [PDF]
da Silva Ribeiro T+8 more
europepmc +1 more source