Results 21 to 30 of about 161,154 (259)

Influence of Convolution Kernel and Beam-Hardening Effect on the Assessment of Trabecular Bone Mineral Density Using Quantitative Computed Tomography [PDF]

open access: yesИзвестия Саратовского университета. Новая серия: Математика. Механика. Информатика, 2020
Quantitative computed tomography along with densitometry is used to assess mineral density and strength of bone tissue. Raw data obtained by computed tomography are converted by software using convolution kernels.
Ivanov, Dmitriy V.   +10 more
doaj   +1 more source

Measuring pulmonary function in COPD using quantitative chest computed tomography analysis

open access: yesEuropean Respiratory Review, 2021
COPD is diagnosed and evaluated by pulmonary function testing (PFT). Chest computed tomography (CT) primarily serves a descriptive role for diagnosis and severity evaluation.
Jens T. Bakker   +3 more
doaj   +1 more source

Diagnostic Efficacy of Quantitative Computed Tomography in CTD-ILA/ILD

open access: yesCT Lilun yu yingyong yanjiu
Objective: The aim of this study is to evaluate the diagnostic efficacy of quantitative computed tomography (CT) in differentiating between connective tissue disease-associated interstitial lung abnormalities (CTD-ILA) and connective tissue disease ...
Ke WANG   +3 more
doaj   +1 more source

Quantitative Computed Tomography and image analysis for advanced muscle assessment

open access: yesEuropean Journal of Translational Myology, 2016
Medical imaging is of particular interest in the field of translational myology, as extant literature describes the utilization of a wide variety of techniques to non-invasively recapitulate and quantity various internal and external tissue morphologies.
Kyle Joseph Edmunds   +5 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Comparison of automated quantification and semiquantitative visual analysis findings of IQ SPECT MPI with conventional coronary angiography in patients with stable angina

open access: yesTürk Kardiyoloji Derneği Arşivi, 2019
Objective: The aim of this study was to assess the validity of automated quantitative and semiquantitative visual analysis of total perfusion deficit (TPD) using the IQ SPECT gamma camera system compared to conventional coronary angiographically detected
Cem Doğan   +13 more
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

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