Results 161 to 170 of about 5,271,287 (215)

Targeted Degradation of Picornaviral 3C Protease via PROTACs Confers High Barrier to Viral Resistance and Broad‐Spectrum Antiviral Activity

Advanced Science, EarlyView.
This study reports D34 as the first PROTAC degrader that targets the 3C protease of picornaviruses. D34 effectively degrades EV71 3C protease via the ubiquitin‐proteasome pathway. More importantly, D34 exhibits a high resistance barrier and shows broad‐spectrum antiviral activity against multiple picornaviruses, highlighting its potential as a novel ...
Weilong Deng, Junyu Chen, Yingyue Pang, Yuanyuan Zhang, Siqian Chen, Guoliang You, Xiaoman Tian, Zhongxin Xu, Jing Wang, Luqing Shang   +9 more
wiley   +1 more source

DHAFGan: A dense hybrid attention fusion generative adversarial network for infrared and visible image fusion. [PDF]

PLoS One
Hong Q, Xu Z, Qin D, Zheng Y, Zhang H.
europepmc   +1 more source

Black Hole Quencher‐Enhanced Plasmonic Photothermal Conversion

Advanced Science, EarlyView.
Researchers have developed a universal method to boost plasmonic photothermal conversion by attaching black hole quencher (BHQ) molecules to matched metal nanostructures. This hybrid approach increases efficiency by roughly threefold, reaching up to 69.1% in the near‐infrared‐II window.
Ruiyuan Zhang, Xinru Chen, Lin Shen, Jin Li   +3 more
wiley   +1 more source

Matrix-based solution methods for deformable derivative systems: applications to growth-decay and mortgage models. [PDF]

Sci Rep
Priya K, Ayman-Mursaleen M, Ujlayan A, Rao N.   +3 more
europepmc   +1 more source

From Displacement to Angle: Diamond‐Based 3D Rotation Sensing for High‐Precision Cellular Force Measurement

Advanced Science, EarlyView.
Cellular forces are traditionally inferred from displacement measurements, which lack rotational information and are constrained by linear model assumptions. This work replaces displacement with rotational angle for the fundamental mechanical readout.
Linjie Ma, Bicong Wang, Tai Nam Yip, Jiahua Zhang, Yicheng Wang, Luyao Zhang, Yong Hou, Yuan Lin, Zhiqin Chu   +8 more
wiley   +1 more source

Breaking the glass ceiling: An interview with Yuhao (Jet) Zhou, María Óskarsdóttir, and Cristián Bravo. [PDF]

Patterns (N Y)
Zhou Y, Óskarsdóttir M, Bravo C.
europepmc   +1 more source

Volatile ZrO2 Antiferroelectric Tunnel Junctions for Rapid, Energy‐Efficient Physical Reservoir Computing

Advanced Science, EarlyView.
An antiferroelectric tunnel junction serves as a reservoir computing node, where field‐induced phase transitions and spontaneous ZrO2 relaxation deliver nonlinear fading memory. An In‐Ga‐Zn oxide interlayer enlarges the memory margin and multibit state richness.
Taegyu Kwon, Moonseek Jeong, Su In Hwang, Geun Hyeong Park, Joonyong Kim, Hyojun Choi, Hyeong Seok Choi, Da Hyun Kim, Dong Hee Han, Ju Yong Park, Seungho Baek, Jung Ho Yoon, Dong Hyun Lee, Min Hyuk Park   +13 more
wiley   +1 more source

Clinical and Translational Science Award hubs in learning health systems: evaluation framework of the engine-drivetrain model. [PDF]

J Transl Med
Ioachimescu OC.
europepmc   +1 more source

Probing Electrocatalyst Design for Product Selectivity in CO2 Reduction

Advanced Science, EarlyView.
Selective CO2 electroreduction is controlled by catalyst structure, dynamic surface reconstruction, adsorbate interactions, and reaction microenvironment. This review summarizes Cu‐ and non‐Cu‐based catalysts, single‐atom and molecular systems, degradation pathways, and operando/computational strategies for steering CO2RR toward hydrocarbons ...
Suvodeep Sen, Bapan Biswas, Apinya Ngoipala, Julia Wiktor, Ujjwal Pal, Shalini Singh   +5 more
wiley   +1 more source

Distinct healing dynamics associated with xenograft selection in guided bone regeneration. [PDF]

Sci Rep
de Sousa YMG, Torres-Silva M, Nunes MAL, Sol I, Lopes JPS, da Silva TGL, Pedrosa MDS, Ponzoni D.   +7 more
europepmc   +1 more source