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The quantitative genetics of transcription
Trends in Genetics, 2005Quantitative geneticists have become interested in the heritability of transcription and detection of expression quantitative trait loci (eQTLs). Linkage mapping methods have identified major-effect eQTLs for some transcripts and have shown that regulatory polymorphisms in cis and in trans affect expression.
Gibson, Greg, Weir, Bruce
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2013
This chapter focuses on quantitative genetics, which analyses the inheritance of complex traits. Complex traits are multifactorial: their expression is influenced by multiple genes and various environmental factors. Most complex traits exhibit continuous phenotypic variation and threshold traits exhibit just two phenotypes.
J. Gai, J. Lu
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This chapter focuses on quantitative genetics, which analyses the inheritance of complex traits. Complex traits are multifactorial: their expression is influenced by multiple genes and various environmental factors. Most complex traits exhibit continuous phenotypic variation and threshold traits exhibit just two phenotypes.
J. Gai, J. Lu
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2020
Quantitative genetics is the study of continuously varying traits which make up the majority of biological attributes of evolutionary and commercial interest. This book provides a much-needed up-to-date, in-depth yet accessible text for the field. In lucid language, the author guides readers through the main concepts of population and quantitative ...
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Quantitative genetics is the study of continuously varying traits which make up the majority of biological attributes of evolutionary and commercial interest. This book provides a much-needed up-to-date, in-depth yet accessible text for the field. In lucid language, the author guides readers through the main concepts of population and quantitative ...
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QUANTITATIVE GENETICS IN PSYCHOLOGY
British Journal of Mathematical and Statistical Psychology, 1971The following paper proposes a simple theoretical model, capable of progressive expansion, to serve as a basis for the statistical investigation of mental inheritance. Formulae are deduced for the analysis of phenotypic variances, and for estimating the covariances and correlations between relatives of different degrees of kinship.
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Quantitative Traits and Quantitative Genetics
2014In contrast with qualitative or dichotomous traits, quantitative traits are measured using quantitative or semi-quantitative variables and their inheritance is controlled by multiple genes acting independently or in association. Quantitative traits are also influenced to varying degrees by the environment and this explains why they are often designated
Jean-Louis Guénet +3 more
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Quantitative genetics: A critique
Social Biology, 1979Abstract The quantitative aspects of human genetics have hitherto been confined to (1) Mendelian categorization of qualities, which is enumerative and best applied to single‐locus conditions; and (2) Galtonian analysis, which is an examination of the first and second moments of quantities and best applied to multiple‐locus conditions.
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2002
Abstract Quantitative genetics has traditionally been based on investigations of continuous or ‘metric’ phenotypes, where there are measurable differences between individuals, rather than on phenotypes that are simply present or absent (Falconer and Mackay 1996).
Alastair Cardno, Peter McGuffin
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Abstract Quantitative genetics has traditionally been based on investigations of continuous or ‘metric’ phenotypes, where there are measurable differences between individuals, rather than on phenotypes that are simply present or absent (Falconer and Mackay 1996).
Alastair Cardno, Peter McGuffin
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2012
AbstractIn this chapter the authors consider the theoretical basis of inheritance and possible sources of phenotypic variation and familial resemblance. The investigation of the genetic basis of psychiatric disorders first requires us to examine to what extent genes and environment contribute to a given disorder or trait.
Anita Thapar, Peter McGuffin
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AbstractIn this chapter the authors consider the theoretical basis of inheritance and possible sources of phenotypic variation and familial resemblance. The investigation of the genetic basis of psychiatric disorders first requires us to examine to what extent genes and environment contribute to a given disorder or trait.
Anita Thapar, Peter McGuffin
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The quantitative genetics of disgust sensitivity.
Emotion, 2016[Correction Notice: An Erratum for this article was reported in Vol 16(1) of Emotion (see record 2015-57029-001). In the article, the name of author Joshua M. Tybur was misspelled as Joshua M. Tyber. All versions of this article have been corrected.] Response sensitivity to common disgust elicitors varies considerably among individuals.
Sherlock, James M. +3 more
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Quantitative Genetics and Mouse Behavior
Annual Review of Neuroscience, 2001▪ Abstract Quantitative differences are observed for most complex behavioral and pharmacological traits within any population. Both environmental and genetic influences regulate such individual differences. The mouse has proven to be a superb model in which to investigate the genetic basis for quantitative differences in complex behaviors. Genetically
J M, Wehner, R A, Radcliffe, B J, Bowers
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