Results 1 to 10 of about 5,789,434 (312)

A bioluminescence reporter mouse model for visualizing and quantifying CD8+ T cells in vivo

Neoplasia: An International Journal for Oncology Research, 2022
Cytotoxic CD8+ T cells are the primary effector cells mediating anti-tumor responses. In vivo monitoring of CD8+ T cells has broad implications for the development of novel cancer therapies.
Kimberly Bettano, Mark Zielstorff, Raquel Sevilla, Ruojing Yang, Heather Zhou, Thomas Rosahl, Jie Zhang-Hoover, Lily Y. Moy, Weisheng Zhang   +8 more
doaj   +1 more source

Hyperdimensional Imaging Contrast Using an Optical Fiber

Sensors, 2021
Fluorescence properties of a molecule can be used to study the structural and functional nature of biological processes. Physical properties, including fluorescence lifetime, emission spectrum, emission polarization, and others, help researchers probe a ...
Jenu V. Chacko, Han Nim Lee, Wenxin Wu, Marisa S. Otegui, Kevin W. Eliceiri   +4 more
doaj   +1 more source

Radiomic Analysis of Multi-parametric MR Images (MRI) for Classification of Parotid Tumors [PDF]

Journal of Biomedical Physics and Engineering, 2022
Background: Characterization of parotid tumors before surgery using multi-parametric magnetic resonance imaging (MRI) scans can support clinical decision making about the best-suited therapeutic strategy for each patient.
Anahita Fathi Kazerooni, Mahnaz Nabil, Mohammadreza Alviri, Soheila Koopaei, Faezeh Salahshour, Sanam Assili, Hamidreza Saligheh Rad, Leila Aghaghazvini   +7 more
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Feasibility of CT-derived myocardial strain measurement in patients with advanced cardiac valve disease

Scientific Reports, 2021
To explore the feasibility of CT-derived myocardial strain measurement in patients with advanced cardiac valve disease and to compare it to strain measurements derived from transthoracic echocardiography (TTE).
Marius Vach, Johanna Vogelhuber, Marcel Weber, Alois M. Sprinkart, Claus C. Pieper, Wolfgang Block, Daniel Kuetting, Ulrike I. Attenberger, Julian A. Luetkens   +8 more
doaj   +1 more source

Longitudinal Evolution of Bone Microarchitecture and Bone Strength in Type 2 Diabetic Postmenopausal Women With and Without History of Fragility Fractures—A 5-Year Follow-Up Study Using High Resolution Peripheral Quantitative Computed Tomography

Frontiers in Endocrinology, 2021
IntroductionDiabetic bone disease is characterized by an increased fracture risk which may be partly attributed to deficits in cortical bone quality such as higher cortical porosity.
Ursula Heilmeier, Ursula Heilmeier, Gabby B. Joseph, Courtney Pasco, Nhan Dinh, Soheyla Torabi, Karin Darakananda, Jiwon Youm, Julio Carballido-Gamio, Andrew J. Burghardt, Thomas M. Link, Galateia J. Kazakia   +11 more
doaj   +1 more source

A Deep Learning Approach for Rapid and Generalizable Denoising of Photon-Counting Micro-CT Images

Tomography, 2023
Photon-counting CT (PCCT) is powerful for spectral imaging and material decomposition but produces noisy weighted filtered backprojection (wFBP) reconstructions.
Rohan Nadkarni, Darin P. Clark, Alex J. Allphin, Cristian T. Badea   +3 more
doaj   +1 more source

Assessment of 3-month changes in bone microstructure under anti-TNFα therapy in patients with rheumatoid arthritis using high-resolution peripheral quantitative computed tomography (HR-pQCT)

Arthritis Research & Therapy, 2017
Background Although one study showed minimal progression of erosions in patients with rheumatoid arthritis (RA) one year after TNFα inhibition therapy, no studies have investigated very early bone changes after initiation of anti-TNFα treatment.
Tomohiro Shimizu, Hyo Jin Choi, Ursula Heilmeier, Matthew Tanaka, Andrew J. Burghardt, Jingshan Gong, Nattagan Chanchek, Thomas M. Link, Jonathan Graf, John B. Imboden, Xiaojuan Li   +10 more
doaj   +1 more source

Investigation of radiomic signatures for local recurrence using primary tumor texture analysis in oropharyngeal head and neck cancer patients

Scientific Reports, 2018
Radiomics is one such “big data” approach that applies advanced image refining/data characterization algorithms to generate imaging features that can quantitatively classify tumor phenotypes in a non-invasive manner.
M. D. Anderson Cancer Center Head and Neck Quantitative Imaging Working Group
doaj   +1 more source

Deep learning supports the differentiation of alcoholic and other-than-alcoholic cirrhosis based on MRI

Scientific Reports, 2022
Although CT and MRI are standard procedures in cirrhosis diagnosis, differentiation of etiology based on imaging is not established. This proof-of-concept study explores the potential of deep learning (DL) to support imaging-based differentiation of the ...
Julian A. Luetkens, Sebastian Nowak, Narine Mesropyan, Wolfgang Block, Michael Praktiknjo, Johannes Chang, Christian Bauckhage, Rafet Sifa, Alois Martin Sprinkart, Anton Faron, Ulrike Attenberger   +10 more
doaj   +1 more source

Deep flow-net for EPI distortion estimation

NeuroImage, 2020
Introduction: Geometric distortions along the phase encoding direction caused by off-resonant spins are a major issue in EPI based functional and diffusion imaging.
Benjamin Zahneisen, Kathrin Baeumler, Greg Zaharchuk, Dominik Fleischmann, Michael Zeineh   +4 more
doaj   +1 more source