Results 201 to 210 of about 2,012,232 (260)

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Fetal Echogenic Bowel: What Is Real Echogenicity? A Quantitative Method Based on Histogram Analysis of the Grayscale.

Fetal Diagn Ther
Spinnato S, De Biase A, Bilardo CM, Elvan-Taşpınar A.   +3 more
europepmc   +1 more source

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Quantitative methods in linguistics

Journal of Quantitative Linguistics, 2010
Johnson, Keith, Quantitative Methods in Linguistics. Malden, MA: Blackwell, 2008. ISBN: 978-1-4051-4424-7, 277 pp.
Emmerich Kelih, Ján Macutek
openaire   +1 more source

Methods in Quantitative Hemagglutinatio

Vox Sanguinis, 1965
SummarySemi‐quantitative methods for measuring the potency of serological reactions are reviewed and particularly compared with the cell counting method of Wilkie and Becker. The Wilkie‐Becker method is highly reproducible and recognizes the importance of the mass action aspects of the hemagglutination reaction first emphasized by Wurmser.The paper ...
Joel M. Solomon, Mary B. Gibbs, A. J. Bowdler   +2 more
openaire   +1 more source

Quantitative molecular methods in virology

Archives of Virology, 1995
During the past few years, significant technical effort was made to develop molecular methods for the absolute quantitation of nucleic acids in biological samples. In virology, semi-quantitative and quantitative techniques of different principle, complexity, and reliability were designed, optimized, and applied in basic and clinical researches.
CLEMENTI M, MENZO S, MANZIN, ALDO, BAGNARELLI P.   +3 more
openaire   +3 more sources

Quantitative methods: producing quantitative methods narratives

Progress in Human Geography, 2003
Recent writings in human geography have claimed that practice of quantitativemethods in the field is retreating as accounts of knowledge move away from metanar-ratives to more discursive practices where sociocultural meanings are seen to beparamount for understanding geographic phenomena. Practitioners of quantitativemethods (QM) in geography have been
openaire   +1 more source

The Lowry Method for Protein Quantitation

1996
The most accurate method of determining protein concentration is probably acid hydrolysis followed by amino acid analysis. Most other methods are sensitive to the amino acid composition of the protein and absolute concentrations cannot be obtained. The procedure of Lowry et al.
J H, Waterborg, H R, Matthews
openaire   +3 more sources

Quantitative Research Methods

Alzheimer Disease & Associated Disorders, 1999
This paper provides some ideas for improving the quality of Alzheimer disease (AD) research projects by using the appropriate quantitative methods. Statistical tests for answering research questions are presented according to the types of design used.
openaire   +2 more sources