Results 251 to 260 of about 3,161,536 (308)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

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Quantitative methods in linguistics

Journal of Quantitative Linguistics, 2010
Johnson, Keith, Quantitative Methods in Linguistics. Malden, MA: Blackwell, 2008. ISBN: 978-1-4051-4424-7, 277 pp.
Emmerich Kelih, Ján Macutek
openaire   +1 more source

Methods in Quantitative Hemagglutinatio

Vox Sanguinis, 1965
SummarySemi‐quantitative methods for measuring the potency of serological reactions are reviewed and particularly compared with the cell counting method of Wilkie and Becker. The Wilkie‐Becker method is highly reproducible and recognizes the importance of the mass action aspects of the hemagglutination reaction first emphasized by Wurmser.The paper ...
Joel M. Solomon, Mary B. Gibbs, A. J. Bowdler   +2 more
openaire   +1 more source

Quantitative molecular methods in virology

Archives of Virology, 1995
During the past few years, significant technical effort was made to develop molecular methods for the absolute quantitation of nucleic acids in biological samples. In virology, semi-quantitative and quantitative techniques of different principle, complexity, and reliability were designed, optimized, and applied in basic and clinical researches.
CLEMENTI M, MENZO S, MANZIN, ALDO, BAGNARELLI P.   +3 more
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Quantitative methods: producing quantitative methods narratives

Progress in Human Geography, 2003
Recent writings in human geography have claimed that practice of quantitativemethods in the field is retreating as accounts of knowledge move away from metanar-ratives to more discursive practices where sociocultural meanings are seen to beparamount for understanding geographic phenomena. Practitioners of quantitativemethods (QM) in geography have been
openaire   +1 more source

The Lowry Method for Protein Quantitation

1996
The most accurate method of determining protein concentration is probably acid hydrolysis followed by amino acid analysis. Most other methods are sensitive to the amino acid composition of the protein and absolute concentrations cannot be obtained. The procedure of Lowry et al.
J H, Waterborg, H R, Matthews
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Quantitative Research Methods

Alzheimer Disease & Associated Disorders, 1999
This paper provides some ideas for improving the quality of Alzheimer disease (AD) research projects by using the appropriate quantitative methods. Statistical tests for answering research questions are presented according to the types of design used.
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Analytical Methods For Quantitation of Methylxanthines

1997
The methylxanthines can be determined in foods and biological systems by the chromatographic methods of TLC, GC, and HPLC. Ultraviolet spectroscopy following a separation procedure is also still used. More recently immunoassay methods have been developed. There is no single best method; the analyst must balance the features of each assay with the final
W J, Hurst, R A, Martin, S M, Tarka
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