Results 51 to 60 of about 1,313,775 (264)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Science, technology, and innovation in health for the next twenty years: A survey analysis in Colombia

Health Care Science
Background Colombia is a Latin American country with a very complex social and political context that has not allowed the allocation of sufficient resources to the fields of science, technology, and innovation (STI). This is particularly worrying for the
Oscar Espinosa, Gabriela Puentes, Jhonathan Rodríguez, Adriana Robayo, Juan‐Manual Anaya   +4 more
doaj   +1 more source

Estimating inequalities in excess mortality and years of potential life lost by health conditions across ethnic minorities in Colombia: a population-based study, 2018-2022

BMJ Open
Objectives This study aims to compare the burden of excess mortality and years of potential life lost by cause of death and geography for minority groups to inform targeted policy development.Design Population-based study using information from the ...
Rocco Friebel, Valeria Bejarano, Oscar Espinosa, Johnattan García-Ruiz   +3 more
doaj   +1 more source

Survey of spatial forms - physical city using quantitative models case study : sardroud city [PDF]

نشریه جغرافیا و برنامه‌ریزی, 2019
Urban growth in itself is a rogue character. We need to harness and guide urban development policy is a great responsibility, because on the one hand and, on the other hand led to eliminate troubles and the emergence of rational longevity of buildings of
rasol gorbani, mahdieh tahooni
doaj  

Quantitative histological models suggest endothermy in plesiosaurs [PDF]

PeerJ, 2018
Background Plesiosaurs are marine reptiles that arose in the Late Triassic and survived to the Late Cretaceous. They have a unique and uniform bauplan and are known for their very long neck and hydrofoil-like flippers.
Corinna V. Fleischle, Tanja Wintrich, P. Martin Sander   +2 more
doaj   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Study on the concentration, distribution, and persistence of health spending for the contributory scheme in Colombia

BMC Health Services Research
Colombia is among the countries with the most robust financial protection against personal health spending in the world, with out-of-pocket spending ranking lowest across OECD countries.
Oscar Espinosa, Rocco Friebel, Valeria Bejarano, Martha-Liliana Arias, Don Husereau, Adrian Smith   +5 more
doaj   +1 more source

Quantitative health impact assessment modelling [PDF]

Scandinavian Journal of Public Health, 2009
Health Impact Assessment (HIA) is spreading as a tool for policy and decision making. An important stage of HIA is to predict the future health consequences of implementing a potential decision in order to raise the level of knowledge for making the final decision. This journal published an editorial on HIA in November 2008 [1]. This editorial expanded
openaire   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Novel human neurodevelopmental and neurodegenerative disease associated with IRF2BPL gene variants—mechanisms and therapeutic avenues

Frontiers in Neuroscience
Recently a broad range of phenotypic abnormalities related to the neurodevelopmental and neurodegenerative disorder NEDAMSS (Neurodevelopmental Disorder with Regression, Abnormal Movements, Loss of Speech, and Seizures) have been associated with rare ...
Daniel Bauersachs, Louise Bomholtz, Sara del Rey Mateos, Ralf Kühn, Pawel Lisowski, Pawel Lisowski   +5 more
doaj   +1 more source