Results 61 to 70 of about 148,622 (246)

Similarity Self/Ideal Index (SSI): A Feature-Based Approach to Modeling Psychological Well-Being

open access: yesMathematics
This paper introduces a similarity index aimed at modeling psychological well-being through a set-theoretic formalization of self–ideal alignment. Inspired by Tversky’s feature-based model of similarity, the proposed index quantifies the degree of ...
Alejandro Sanfeliciano   +3 more
doaj   +1 more source

Continuous Predictors of Pretest-Posttest Change: Highlighting the Impact of the Regression Artifact

open access: yesFrontiers in Applied Mathematics and Statistics, 2019
Researchers are often interested in exploring predictors of change, and commonly use a regression based model or a gain score analysis to compare degree of change across groups.
Linda Farmus   +2 more
doaj   +1 more source

Lactate‐Driven Restriction of Mitochondrial Permeability Transition Promotes Resistance to Chemo‐Immunotherapy by Suppressing Tumor PANoptosis

open access: yesAdvanced Science, EarlyView.
Tumor‐derived lactate establishes a metabolic lock that drives chemo‐immunotherapy resistance by suppressing PANoptosis. Mechanistically, KAT8 lactylates the mitochondrial translocator ANT2, which recruits PGAM5 to dephosphorylate CypD. This cascade restricts mitochondrial permeability transition pore opening, preventing pro‐inflammatory mtDNA leakage.
Sen Zhong   +20 more
wiley   +1 more source

Sudden transition to online learning: Exploring the relationships among measures of student experience

open access: yesInternational Journal of Educational Research Open
Online learning anxiety might be related to how university students perceived their learning and performance during the COVID-19 pandemic, and in course modules with mathematical content, math anxiety may also have come into play.
Roser Bono   +4 more
doaj   +1 more source

Psychological Stress Associated Bile Acid Reprogramming Promotes Hepatocellular Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng   +10 more
wiley   +1 more source

Computational protocol for hierarchical Bayesian modeling of perception and generalization in fear conditioning

open access: yesSTAR Protocols
Summary: Understanding human generalization behavior requires disentangling underlying cognitive and perceptual mechanisms. Here, we present a computational protocol to analyze individual differences in fear generalization by integrating a Bayesian state-
Kenny Yu   +3 more
doaj   +1 more source

Paternal Sperm Gnas‐ICR Epigenetic Programming Contributes to PPP‐Like Phenotypes in Female Offspring

open access: yesAdvanced Science, EarlyView.
A paternal glucocorticoid–sperm Gnas‐ICR axis is linked to ovarian endocrine programming in female offspring. Paternal preconception caffeine exposure elevates corticosterone, promotes sperm Gnas‐ICR hypermethylation, and is associated with ovarian Gnas upregulation, cAMP/PKA/CREB–StAR activation, enhanced estradiol synthesis, and PPP‐like phenotypes ...
Jing Huang   +4 more
wiley   +1 more source

Possession in Football: More Than a Quantitative Aspect – A Mixed Method Study

open access: yesFrontiers in Psychology, 2019
The aim of the present study was to identify and differentiate the factors that determine the possession times of successful and unsuccessful elite football teams, with the purpose of identifying a more effective possession model.
Claudio A. Casal   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy