Results 131 to 140 of about 19,357,515 (242)

Evaluation of Cx43 Gap Junction Inhibitors Using a Quantitative Structure-Activity Relationship Model. [PDF]

Biomedicines, 2023
Matusevičiūtė R, Ignatavičiūtė E, Mickus R, Bordel S, Skeberdis VA, Raškevičius V.   +5 more
europepmc   +1 more source

Rheumatoid Arthritis and Coronary Artery Calcium Progression: A Case Cohort Analysis From ELSA‐Brasil

Arthritis Care &Research, EarlyView.
Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada, Marcos Rafael N. Cavalcante, Itamar de Souza Santos, Márcio S. Bittencourt, Vandrize Meneghini, Paulo A. Lotufo, Alessandra C. Goulart, Isabela M. Bensenor   +7 more
wiley   +1 more source

Machine learning-based quantitative structure-activity relationship model for antibiotic prediction and discovery. [PDF]

PLOS Digit Health
Nakbang J, Arbsuwan C, Prom-On S, Chienwichai P.   +3 more
europepmc   +1 more source

Dataset on aquatic ecotoxicity predictions of 2697 chemicals, using three quantitative structure-activity relationship platforms. [PDF]

Data Brief, 2023
Svedberg P, Inostroza PA, Gustavsson M, Kristiansson E, Spilsbury F, Backhaus T.   +5 more
europepmc   +1 more source

Structural evolution of quinine derivatives for enhanced antifungal potency: key modifications and quantitative structure-activity relationship (QSAR) analysis. [PDF]

Pest Manag Sci
Fan L, Wu Y, Lei Y, Liu Y, Li M, Chen C, Zhang H, Shi L, Peng J.   +8 more
europepmc   +1 more source

Quantitative Structure-Activity Relationship in the Series of 5-Ethyluridine, N2-Guanine, and 6-Oxopurine Derivatives with Pronounced Anti-Herpetic Activity. [PDF]

Molecules, 2023
Khairullina V, Martynova Y.
europepmc   +1 more source

Engagement Patterns With an Artificial Intelligence Health Coach for Systemic Sclerosis Self‐Management: A Mixed Methods Study

Arthritis Care &Research, EarlyView.
Objective To evaluate utility of an artificial intelligence (AI) health coach for systemic sclerosis (SSc) self‐management and identify patterns associated with participant engagement. Methods We conducted a mixed methods study in which an AI health coach, powered by a large language model (LLM), was used to support self‐management for SSc.
Nirali Shah, Melanie Morris, Cristina Daraban, Sophia Johnson, Susan L. Murphy   +4 more
wiley   +1 more source

Quantitative structure-activity relationship study of amide derivatives as xanthine oxidase inhibitors using machine learning. [PDF]

Front Pharmacol, 2023
Yang X, Qiu H, Zhang Y, Zhang P.
europepmc   +1 more source

Beyond Visual Scoring: Computational Computed Tomography Analysis for High‐Resolution Computed Tomography–Based Quantification of Interstitial Lung Disease in Inflammatory Rheumatic Disease

Arthritis Care &Research, EarlyView.
Interstitial lung disease (ILD) is a significant cause of morbidity and mortality in patients with inflammatory rheumatic disorders (IRDs). High‐resolution computed tomography (HRCT) is widely considered the gold standard for the noninvasive assessment of ILD; however, its interpretation is constrained by substantial interobserver variability and the ...
Alexander Pfeil, Tobias Hoffmann, Ulf Teichgräber, Diane Renz, Denise Beckmann, Gunter Wolf, Nicole Schadewaldt, Bianca Lassen‐Schmidt   +7 more
wiley   +1 more source

Data-Driven Quantitative Structure-Activity Relationship Modeling for Human Carcinogenicity by Chronic Oral Exposure. [PDF]

Environ Sci Technol, 2023
Chung E, Russo DP, Ciallella HL, Wang YT, Wu M, Aleksunes LM, Zhu H.   +6 more
europepmc   +1 more source