Results 61 to 70 of about 822,154 (239)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Evaluating whether a change in organisational structure would improve its competitive advantage [PDF]
, 2017 The purpose of this research is to study and analyse the internal and external structure of Ultimate Clean ltd, where I do work. We have put concentration on background of the company in the starting.
Kaur, Sarbjeet, Mather, Geoffrey
core
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
On distance-based indices of regular dendrimers using automorphism group action
Main Group Metal Chemistry, 2023 The various topological indices are helpful in predicting the bioactivity of molecular compounds in quantitative structure–activity relationship/quantitative structure–property relationship study. The Balaban index and Harary index are the distance-based
Ahmad Uzma +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Friction, 2023 Development of energy-efficient lubricants is a way to reduce energy consumption for transportation, with the tendency to design molecules that are beneficial in reducing the viscosity of synthetic oils. Oligoether esters (OEEs), as a low-viscosity ester
Hanwen Wang +6 more
doaj +1 more source
Qualitative Theory and Chemical Explanation [PDF]
, 2002 Roald Hoffmann and other theorists claim that we we ought to use highly idealized chemical models (``qualitative models'') in order to increase our understanding of chemical phenomena, even though other models are available which make more highly ...
Weisberg, Michael
core
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Applied Sciences, 2018 A quantitative structure-property relationship (QSPR) model is proposed to explore the relationship between the pKa of various compounds and their structures. Through QSPR studies, the relationship between the structure and properties can be obtained. In
Mengshan Li +5 more
doaj +1 more source