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Heritability estimation of sex‐specific effects on human quantitative traits
Genetic Epidemiology, 2007AbstractRecent studies have suggested that sex‐specific genetic architecture could be because of the effects of autosomal genes that are differentially expressed in males and females. Yet, few studies have explored the effects of X‐linked genes on sex‐specific genetic architecture.
Lin, Pan, Carole, Ober, Mark, Abney
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Human Heredity, 1993
Methods to determine the proportion of variability manifested by a quantitative trait that is attributable to additive genetic effects are important tools for human population and statistical geneticists. Though traditional methods based on parent-offspring and sib-pair correlations have been well researched, they are being steadily supplanted or ...
N J, Schork, M A, Schork
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Methods to determine the proportion of variability manifested by a quantitative trait that is attributable to additive genetic effects are important tools for human population and statistical geneticists. Though traditional methods based on parent-offspring and sib-pair correlations have been well researched, they are being steadily supplanted or ...
N J, Schork, M A, Schork
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Heritabilities and quantitative trait loci for blood gases and blood pH in swine
Animal Genetics, 2009SummaryMaintaining pH and blood gases in a narrow range is essential to sustain normal biochemical reactions. Decreased oxygenation, poor tissue perfusion, disturbance to CO2 expiration, and shortage of HCO3− can lead to metabolic acidosis. This is a common situation in swine, and originates from a broad range of medical conditions.
G, Reiner +5 more
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Heritability of quantitative orbital traits.
Human biology, 1990We conducted a study of 63 couples and their 242 normal children from northeastern Brazil (no facial malformations or deformities) to evaluate the heritability of 4 quantitative traits of the orbital region adjusted by covariance for sex, age, (age)2, sex x age, and sex x (age)2.
C M, Raposo-do-Amaral +3 more
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Principal Components of Heritability for High Dimension Quantitative Traits and General Pedigrees
Statistical Applications in Genetics and Molecular Biology, 2012For many complex disorders, genetically relevant disease definition is still unclear. For this reason, researchers tend to collect large numbers of items related directly or indirectly to the disease diagnostic. Since the measured traits may not be all influenced by genetic factors, researchers are faced with the problem of choosing which traits or ...
Oualkacha, Karim +4 more
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American Journal of Medical Genetics, 2002
AbstractDespite evidence for several chromosomal loci linked to schizophrenia, no susceptibility genes have been identified for the disorder. Using quantitative measures of phenotypic affection in place of clinical diagnostic categories or dichotomous classification of the affection status may be more effective in searching for susceptibility genes ...
Annamari, Tuulio-Henriksson +8 more
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AbstractDespite evidence for several chromosomal loci linked to schizophrenia, no susceptibility genes have been identified for the disorder. Using quantitative measures of phenotypic affection in place of clinical diagnostic categories or dichotomous classification of the affection status may be more effective in searching for susceptibility genes ...
Annamari, Tuulio-Henriksson +8 more
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Heritability of quantitative traits
1995Abstract In the most traditional view, heritability is the proportion of total phenotypic variance attributable to additive genetic variance. The latter results from segregation of alleles with additive effects. Other contributors to total variance include dominance, epistatic and environmental effects and covariances and interactions ...
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Quantitative genetics of cranial nonmetric traits in randombred mice: Heritability and etiology
American Journal of Physical Anthropology, 1986AbstractCheverud and Buikstra (1981) demonstrated a tendency for nonmetric traits representing the number of foramina to have lower heritabilities than those representing hyperstotic or hypostotic traits in a sample of rhesus macaques. Based on this observation, Cheverud and Buikstra hypothesize that differences in the heritability of the two sets of ...
J T, Richtsmeier, J W, McGrath
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Heritability of some quantitative traits in winter wheat
1998Broad and narrow sense heritability estimates were otained for 11 traits in 15 winter wheat combinations of crossing (Triticum aestivum L.) In seven combinations of crossing a high mean value was found for a large number of traits and moderately high to high broad and/or narrow sense heritability estimates.
Kozumplik, Vinko +3 more
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American Journal of Physical Anthropology, 1981
AbstractThe use of skeletal nonmetric traits in studies of biological relationships often involves the assumption that variation in these traits is genetic. Studies of nonmetric traits in human groups and in inbred strains of mice and rabbits have indicated a genetic component to nonmetric trait variation.
J M, Cheverud, J E, Buikstra
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AbstractThe use of skeletal nonmetric traits in studies of biological relationships often involves the assumption that variation in these traits is genetic. Studies of nonmetric traits in human groups and in inbred strains of mice and rabbits have indicated a genetic component to nonmetric trait variation.
J M, Cheverud, J E, Buikstra
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