Results 121 to 130 of about 361,741 (406)

Quantitative Trait Locus Mapping of Melanization in the Plant Pathogenic Fungus Zymoseptoria tritici

G3: Genes, Genomes, Genetics, 2014
Melanin plays an important role in virulence and antimicrobial resistance in several fungal pathogens. The wheat pathogen Zymoseptoria tritici is important worldwide, but little is known about the genetic architecture of pathogenicity, including the ...
M. Lendenmann, D. Croll, Ethan L. Stewart, B. McDonald   +3 more
semanticscholar   +1 more source

Successful Hunt for Quantitative Trait Locus in Thrombophilia [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2003
In recent years, our knowledge of the genetic mechanisms of thrombophilia has advanced considerably. The elucidation of the protein C system with the identification of protein C and protein S deficiencies and activated protein C (APC) resistance due to a factor V gene mutation (FV Leiden) as major risk factors of thrombosis has been instrumental for ...
openaire   +2 more sources

De Novo Reconstruction of 3D Human Facial Images from DNA Sequence

Advanced Science, EarlyView.
This study introduces Difface, a novel deep‐learning model for reconstructing 3D facial images only from DNA data. By integrating transformer networks, spiral convolutions, and a diffusion model, Difface directly aligns high‐dimensional SNP data with 3D facial structures.
Mingqi Jiao, Jiarui Li, Bingxu Zhong, Siyuan Du, Shuning Li, Manfei Zhang, Qibin Zhang, Zhongming Liang, Fan Liu, Chunman Zuo, Sijia Wang, Luonan Chen   +11 more
wiley   +1 more source

A New Advanced Backcross Tomato Population Enables High Resolution Leaf QTL Mapping and Gene Identification. [PDF]

, 2016
Quantitative Trait Loci (QTL) mapping is a powerful technique for dissecting the genetic basis of traits and species differences. Established tomato mapping populations between domesticated tomato (Solanum lycopersicum) and its more distant interfertile ...
Chitwood, Daniel H, Covington, Michael F, Fulop, Daniel, Headland, Lauren, Ichihashi, Yasunori, Maloof, Julin N, Ofner, Itai, Ranjan, Aashish, Sinha, Neelima R, West, Donelly, Zamir, Daniel   +10 more
core   +3 more sources

M2 Macrophage‐Derived Extracellular Vesicles Reprogram Immature Neutrophils into Anxa1hi Neutrophils to Enhance Inflamed Bone Regeneration

Advanced Science, EarlyView.
This study reveals that M2‐EVs mitigate periodontitis‐induced bone resorption by modulating neutrophil fate. Single‐cell RNA sequencing identified an Anxa1hi neutrophil subpopulation with pro‐reparative properties. M2‐EVs disrupt neutrophil maturation, promoting this subpopulation through key reprogramming genes (Acvrl1, Fpr2). These findings highlight
Yufei Yao, Yijia Yin, Fangyuan Shuai, Waishan Lam, Tao Zhou, Yaxin Xie, Xuesong He, Xianglong Han   +7 more
wiley   +1 more source

Evolution of assortative mating in a population expressing dominance.

PLoS ONE, 2011
In this article, we study the influence of dominance on the evolution of assortative mating. We perform a population-genetic analysis of a two-locus two-allele model.
Kristan A Schneider, Stephan Peischl
doaj   +1 more source

A complete classification of epistatic two-locus models [PDF]

arXiv, 2006
The study of epistasis is of great importance in statistical genetics in fields such as linkage and association analysis and QTL mapping. In an effort to classify the types of epistasis in the case of two biallelic loci Li and Reich listed and described all models in the simplest case of 0/1 penetrance values.
arxiv  

The evolution of genetic architectures underlying quantitative traits

, 2013
In the classic view introduced by R. A. Fisher, a quantitative trait is encoded by many loci with small, additive effects. Recent advances in QTL mapping have begun to elucidate the genetic architectures underlying vast numbers of phenotypes across ...
Plotkin, Joshua B., Rajon, Etienne
core   +1 more source

Quantitative trait locus analysis of resistance to panicle blast in the rice cultivar Miyazakimochi

Rice, 2014
BackgroundRice blast is a destructive disease caused by Magnaporthe oryzae, and it has a large impact on rice production worldwide. Compared with leaf blast resistance, our understanding of panicle blast resistance is limited, with only one panicle blast
T. Ishihara, Y. Hayano-Saito, Shinichi Oide, K. Ebana, N. T. La, K. Hayashi, T. Ashizawa, F. Suzuki, S. Koizumi   +8 more
semanticscholar   +1 more source

LncRNA‐MEG3 Regulates Muscle Mass and Metabolic Homeostasis by Facilitating SUZ12 Liquid–Liquid Phase Separation

Advanced Science, EarlyView.
This study has identified lncRNA‐MEG3 as a key regulator of muscle mass, promoting slow‐twitch muscle fibers and preventing muscle atrophy. By stabilizing the SUZ12/PRC2 complex through liquid–liquid phase separation (LLPS), lncRNA‐MEG3 influences mitochondrial function and lipid metabolism.
Yilong Yao, Chao Yan, Haibo Huang, Shilong Wang, Jiaying Li, Yun Chen, Xiaolu Qu, Qi Bao, Lingna Xu, Yuanyuan Zhang, Danyang Fan, Xia He, Yanwen Liu, Yongsheng Zhang, Yalan Yang, Zhonglin Tang   +15 more
wiley   +1 more source