Results 11 to 20 of about 299,494 (283)
Combined expression trait correlations and expression quantitative trait locus mapping. [PDF]
PLoS Genetics, 2006 Coordinated regulation of gene expression levels across a series of experimental conditions provides valuable information about the functions of correlated transcripts.
Hong Lan +12 more
doaj +6 more sources
Complex genetic interactions in a quantitative trait locus. [PDF]
PLoS Genetics, 2006 Whether in natural populations or between two unrelated members of a species, most phenotypic variation is quantitative. To analyze such quantitative traits, one must first map the underlying quantitative trait loci.
Himanshu Sinha +3 more
doaj +5 more sources
Multiple-trait quantitative trait locus mapping with incomplete phenotypic data [PDF]
BMC Genetics, 2008 Background Conventional multiple-trait quantitative trait locus (QTL) mapping methods must discard cases (individuals) with incomplete phenotypic data, thereby sacrificing other phenotypic and genotypic information contained in the discarded cases. Under
Guo Zhigang, Nelson James C
doaj +3 more sources
The Dissection of Expression Quantitative Trait Locus Hotspots [PDF]
Genetics, 2015 Studies of the genetic loci that contribute to variation in gene expression frequently identify loci with broad effects on gene expression: expression quantitative trait locus hotspots.
Jianan Tian +6 more
semanticscholar +5 more sources
A hierarchical Bayesian approach to multi-trait clinical quantitative trait locus modeling [PDF]
Frontiers in Genetics, 2012 Recent advances in high-throughput genotyping and transcript profiling technologies have enabled the inexpensive production of genome-wide dense marker maps in tandem with huge amounts of expression profiles.
Crispin M. Mutshinda +3 more
doaj +3 more sources
Expression quantitative trait locus analysis for translational medicine
Genome Medicine, 2015 Expression quantitative trait locus analysis has emerged as an important component of efforts to understand how genetic polymorphisms influence disease risk and is poised to make contributions to translational medicine.
G. Gibson, J. Powell, U. Marigorta
semanticscholar +4 more sources
R/qtlcharts: Interactive Graphics for Quantitative Trait Locus Mapping [PDF]
Genetics, 2014 Every data visualization can be improved with some level of interactivity. Interactive graphics hold particular promise for the exploration of high-dimensional data.
K. Broman
semanticscholar +4 more sources
Nature Genetics, 2023 Brain expression quantitative trait locus (eQTL) and network analyses encompassing 8,613 RNA-sequencing samples from 14 eQTL datasets reveal downstream effects and putative drivers for brain-related diseases.
N. de Klein +19 more
semanticscholar +1 more source