Results 141 to 150 of about 3,086 (259)
Integrative Zoology, EarlyView.A quantum‐enhanced weighted gene co‐expression network analysis framework integrating quantum amplitude amplification is developed to overcome sample size constraints in zoological genomics. This noise‐tolerant analytical strategy enables robust network reconstruction for non‐model species with limited biological replicates.
Seok‐Jin Kang, Hongchul Shin
wiley +1 more source
Global Policy, EarlyView.ABSTRACT This article examines the evolution of European Union (EU) space policy through the lens of historical institutionalism, highlighting how security and defence considerations have been incrementally integrated into a domain originally framed as civilian and scientific.
Gustavo G. Müller, Philip De Man
wiley +1 more source
Global Policy, EarlyView.ABSTRACT This article examines the EU's evolving narratives concerning the governance of digital technologies, focusing on the intersection of geopolitical challenges and internal policymaking through the lens of the strategic narratives approach. This compares two key EU narratives relating to digital policy: on the one hand, the narrative on ‘digital
Flavia Lucenti +4 more
wiley +1 more source
The Great Cosmic Silence: What Does the Fermi Paradox Tell About the Future of Humanity?
Global Policy, EarlyView.ABSTRACT This article examines how institutional time horizons shape the long‐term survival prospects of human technological civilisation. While research on global catastrophic and existential risks has expanded, the temporal structures of political‐economic institutions remain underexamined.
Heikki Patomäki
wiley +1 more source
Addiction, EarlyView.Abstract Background and aims This study qualitatively explored psychological change processes as described by participants and therapists within a phase 2a clinical trial evaluating the safety, tolerability, and preliminary efficacy of a single dose of intranasal 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT; BPL‐003) administered alongside psychological
Mathieu Seynaeve +6 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose In contrast to neurons in the central nervous system, neurons in the peripheral nervous system can regenerate axons after injury via activation of a pro‐regenerative transcriptional programme. Pathogenic mutations in leucine‐rich repeat kinase 2 (LRRK2) are the most common genetic cause of Parkinson's disease, and several small ...
Eun‐Hae Jang +11 more
wiley +1 more source
Difference and the Liberation of Sufficient Reason
European Journal of Philosophy, EarlyView.Abstract The Principle of Sufficient Reason (PSR) holds that every event and entity can be explained by a sufficient reason or cause. Philosophers have long struggled with the question of the PSR's compatibility with freedom, for if what occurs or exists follows necessarily from its sufficient reason then it seems it could not have been otherwise ...
Louis Matheou
wiley +1 more source
Kojève's silence: science and the end of history. [PDF]
Cont Philos Revvan Gemert T.
europepmc +1 more source
The Nature of Causality in Quantum Phenomena
, 2000 The correlations between distant systems in typical quantum situations, such as Einstein-Podolosky-Rosen experiments, strongly suggest that the quantum realm involves curious types of non-local influences. In this paper, I study in detail the nature of these non-local influences, as depicted by various quantum theories.
openaire +2 more sources
The R203W substitution drives PACS‐1 syndrome by disrupting intramolecular regulation
The FEBS Journal, EarlyView.The middle region (MR) of PACS‐1 controls engagement with specific partner proteins. This manuscript presents the structure of the Furin binding region (FBR) and how interactions with partners are regulated through the interplay between a basic patch in the FBR and an acidic cluster in the MR.
Troy C. Krzysiak +7 more
wiley +1 more source