Results 221 to 230 of about 25,058 (296)

Molecular‐Scale Tuning of Low‐Molecular‐Weight Gelators Controls Supramolecular Assembly and Directs Human Mesenchymal Stem Cell Growth

open access: yesAngewandte Chemie, EarlyView.
Chemistry in charge of biology! Simple low‐molecular‐weight gelators, with minor modifications in molecular structure, self‐assemble differently and can also co‐assemble when simultaneously triggered. This creates a family of gels with different properties that direct the growth of stem cells in different ways.
Chayanan Tangsombun   +5 more
wiley   +2 more sources

Soft Artificial Ciliary Brush with Integrated Haptic Feedback for Efficient Airway Mucus Cleaning

open access: yesAdvanced Intelligent Systems, EarlyView.
A fundamental mucus cleaning mechanism is reported, which utilizes both artificial cilia mechanical sweeping and suction‐based mucus cleaning. A novel haptic feedback interface for the artificial cilia provides touch feedback on tissue contact, enhancing operator control and safety.
Zhongming Lyu   +7 more
wiley   +1 more source

Transforming RNA Degradation into Accurate RNA Detection: RNase I–Assisted Rolling Circle Amplification for Clinical Samples

open access: yesAngewandte Chemie, EarlyView.
Here, we transform this otherwise destructive enzymatic activity into a powerful diagnostic advantage through an RNase I–assisted rolling circle amplification (RI‐RCA) strategy. By integrating controlled RNase I–mediated RNA digestion with circular DNA templates, this approach enables direct and highly sensitive detection of target RNA sequences. Using
Amal Mathai   +5 more
wiley   +2 more sources

Protecting quantum entanglement from leakage and qubit errors via repetitive parity measurements. [PDF]

open access: yesSci Adv, 2020
Bultink CC   +11 more
europepmc   +1 more source

PCA‐Based Database Mining Enables the Discovery of Bacterial Carbene Transferases for Stereodivergent Cyclopropanation

open access: yesAngewandte Chemie, EarlyView.
Database mining using principal component analysis (PCA)‐based clustering enabled discovery of bacterial enzymes capable of catalyzing stereodivergent cyclopropanation of styrene. Statistical analyses of sequence data further revealed characteristic structural properties of these enzymes, highlighting the potential of the bioinformatics tools for ...
Shunsuke Kato   +5 more
wiley   +2 more sources

Modular Assembly of Dynamic Polymer Networks From Heteroaffinity Cross‐Links to Multivalent Proteins

open access: yesAngewandte Chemie, EarlyView.
This study develops a method to modularly assemble oligomeric binding proteins, like streptavidin, using heterobifunctional cross‐linkers that have both a strong‐ and a weak‐affinity binding moiety. These dynamic cross‐linkers enable the assembly of polymer networks with unique meta‐stable nonequilibrium topologies, and that exhibit chemically tunable ...
Tianyue Dai   +6 more
wiley   +2 more sources

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