Results 211 to 220 of about 40,499 (317)

T cell plasticity in systemic lupus erythematosus revealed by large‐scale T cell receptor repertoire and transcriptome studies

open access: yesArthritis &Rheumatology, Accepted Article.
Objective We aimed to characterize CD4+ T cell plasticity in human SLE by leveraging TCR repertoire features as markers of prior lineage states, integrating TCR and transcriptomic profiling to delineate plasticity patterns and evaluate their association with clinical disease activity.
Yasuo Nagafuchi   +11 more
wiley   +1 more source

Addressing Small Data Challenges in Biopharmaceutical Development and Manufacturing: A Mini Review of Multi‐Fidelity Techniques

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT The growing demand for biopharmaceutical products reflects their effectiveness in medical treatments. However, developing new biopharmaceuticals remains a major bottleneck, often taking up to a decade before market approval. Machine learning (ML) models have the potential to accelerate this process, but their success depends on access to large
Mohammad Golzarijalal   +2 more
wiley   +1 more source

Sometimes Hot, Sometimes Not: The Relations Between Selected Situational Vocational Interests and Situation Perception

open access: yesEuropean Journal of Personality, EarlyView., 2020
Abstract Vocational interests are traditionally conceived as stable preferences for different activities. However, recent theorizing suggests their intraindividual variability. This preregistered experience sampling study examined intraindividual variation in selected vocational interests states and related situation and person factors (N = 237 ...
Lena Roemer   +3 more
wiley   +1 more source

Quantum benchmarking of high-fidelity noise-biased operations on a detuned Kerr-cat qubit. [PDF]

open access: yesProc Natl Acad Sci U S A
Qing B   +21 more
europepmc   +1 more source

Green Innovation and Firm Efficiency: The Role of Institutional Quality in Italian High‐Tech Manufacturing Sectors

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT The aim of this research is to verify whether institutional quality affects the relationship between green innovation and firm efficiency within the high‐tech manufacturing sectors. To estimate jointly the parameters of a stochastic frontier and the coefficients of a model explaining technical inefficiency, we employed the one‐step estimation ...
Mariarosaria Agostino   +2 more
wiley   +1 more source

Learning to decode logical circuits. [PDF]

open access: yesNat Comput Sci
Zhou Y   +5 more
europepmc   +1 more source

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