Results 241 to 250 of about 5,684,589 (342)

Predicting the distribution of <i>Sphagna</i> (Bryophyta) in Türkiye: a perspective of present and future climate scenarios. [PDF]

Front Plant Sci
Abay G, Gül S.
europepmc   +1 more source

Scaffolding Protein ENH Promotes Tumor Angiogenesis and Growth Through Macrophage Recruitment and Polarization

Advanced Science, EarlyView.
In tumor cells, ENH prompts the interaction between YAP and KPNA2. This interaction enables YAP to translocate into the nucleus, where it enhances the transcription of CCL5. Consequently, this up‐regulation of CCL5 drives the infiltration of tumor‐associated macrophages (TAMs) and their polarization toward the M2 phenotype, ultimately facilitating ...
Yueli Shi, Zhiyong Xu, Huan Wang, Bufu Tang, Nueraili Maihemuti, Xinyuan Jiang, Xiuying Chen, Mingshu Xiao, Sujing Jiang, Yun Xu, Peng Xiao, Jiangnan Zhao, Kaiyue Zhang, Mengshu Li, Kai Wang   +14 more
wiley   +1 more source

Safety and immunogenicity of fractional COVID-19 vaccine doses in Nigerian adults: A randomized non-inferiority trial. [PDF]

Sci Rep
Salako A, Musa A, Ige F, Abdullahi A, James A, Ekama S, Odubela O, Idigbe I, Ajibaye O, Mazharul A, Adeneye K, Akinsolu FT, Olojo I, Okwuraiwe A, Egharevba H, Ekpenyong M, Elemuwa U, Ezenyi I, Bitrus F, Odubela O, Oba A, Idris G, Yusuf J, Akande I, Nwaiwu S, Omale L, Oyewunmi O, Agbabiaka A, Eyinade O, Ogunwale J, Garba A, Bello Y, Musa B, Ezejiofor O, Ejiro B, Iwalokun B, Rosenzweig L, Adigwe O, Adeyeye C, Shuaib F, Wicek W, Hamada Y, Ezechi O, Gupta R, Salako B.   +44 more
europepmc   +1 more source

Restoration of SIRT3 Expression in Aged Mice Alleviates UUO‐Induced Renal Fibrosis by Reducing GSK‐3β Hyperacetylation

Advanced Science, EarlyView.
SIRT3 expression is significantly downregulated in the aged kidney, rendering the kidney more vulnerable to fibrotic changes in obstructive nephropathy. By promoting GSK‐3β deacetylation, SIRT3 indirectly inhibits Wnt/β‐catenin signaling, thereby suppressing renal fibrosis.
Jing Wang, Xiang Ren, Huan Lu, Zihao Guo, Xing Li, Yiqun Tian, Yisheng Yin, Zhenliang Qin, Kun Yun, Minglong Wu, Gang Chen, Xiaoyong Zeng   +11 more
wiley   +1 more source

Trends in Suspected Fentanyl-Involved Nonfatal Overdose Emergency Department Visits, by Age Group, Sex, and Race and Ethnicity - United States, October 2020-March 2024. [PDF]

MMWR Morb Mortal Wkly Rep
Pickens CM, Park J, Casillas SM, Liu S, Sheppard M, Stokes EK, Ko JY, Lee SH.   +7 more
europepmc   +1 more source

Exosomes From Intestinal Epithelial Cells Promote Hepatic Differentiation of Liver Progenitor Cells in Gut‐Liver‐on‐a‐Chip Models

Advanced Science, EarlyView.
The effects of intestinal epithelial cells and their exosomes on the hepatic differentiation of HPCs are explored in a gut‐liver‐on‐a‐chip. Exosomes from intestinal epithelial cells improve liver fibrosis. Moreover, the miR‐371‐373 cluster in the exosomes may mediate this effect by regulating the hepatic differentiation of HPCs.
Liang Ye, Shi Li, Guofang Bi, Binghui Li, Zhai Cai, Meixian Jin, Ying Zhang, Wanren Yang, Yang Li, Shao Li, Wei Hu, Yi Gao, Mingxin Pan, Shuqin Zhou, Chao Zhang, Huichang Bi, Qing Peng   +16 more
wiley   +1 more source

Sociodemographic patterns of provider-to-home telehealth use within the veterans health administration between 2015 and 2023. [PDF]

Discov Health Syst
Dardashti N, Ferguson JM, Nicholson A, Heyworth L, Hogan TP, McMahon N, Slightam C, Zulman DM, Sherman SE.   +8 more
europepmc   +1 more source

Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study)

Advanced Science, EarlyView.
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang, Lixia Song, Rui Fan, Qianqian Chen, Ruisheng Fu, Mei You, Yuxiao Wu, Meng Cai, Yong Li, Meihong Xu   +9 more
wiley   +1 more source

Continuous decline of climate fluctuations in the Kunlun-Pamir Plateau from the perspective of the bioclimatic variables. [PDF]

Sci Rep
Huang X, Bao A, Wu Y, Zheng G, Yu T, Yuan Y, Li T, Wang T, Zheng L, Jiang L, Bao J, Nzabarinda V, De Maeyer P, Van de Voorde T.   +13 more
europepmc   +1 more source

Delivery of Molecular Hydrogen for Precision Immunomodulation: Mechanisms, Detection Methods, and Applications

Advanced Science, EarlyView.
This review focuses on the immunomodulatory mechanisms of molecular hydrogen, the recent detection methods, and the classification advanced molecular hydrogen delivery materials. It provides a detailed description of their applications in areas such as arthritis, chronic wounds, cardiovascular injury, tumors, and bacterial infections, aiming to enhance
Gangfeng Li, Hannan Cui, Ruixiao Fan, Guming Liu, Zishuo Hou, Yibo Zhang, Xuanming Che, Tengjiao Wang, Hongbo Wei, Peng Li   +9 more
wiley   +1 more source