Results 31 to 40 of about 216,809 (266)
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Journal of Dairy Science: Staphylococcal species are frequently isolated from dairy cow milk and are a very common cause of IMI. First-lactation cows may already have an IMI at calving, and these may be acquired during different stages of their development.
Daryna Kurban +9 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Forecasting the leverage listed companies in Tehran Stock Exchange with the help of simulating models [PDF]
تحقیقات مالی, 2017 Reviewing trend and forecasting the debt ratio is one of the attractive topics for investors, managers, financial analysts and creditors. In this research, in order to forecasting debt ratio for listed companies in Tehran Stock Exchange, target leverage ...
Mohammad Osoolian, Aijamal Kor
doaj +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Trends in hepatocellular carcinoma incident cases in Japan between 1996 and 2019
Scientific Reports, 2022 We examined the epidemiological trends, including the distribution of sex, age, and disease etiology, in HCC incident cases, over 24 years. Data of 20,547 HCC patients (1996–2019) were analyzed in this prospective study.
Masahito Nakano +27 more
doaj +1 more source
Annals of Surgery Open, 2021 Objective:. To examine possible associations in inpatient healthcare expenditure and guideline changes in the surgical management of diverticulitis, in terms of both cost per discharge and total aggregate costs of care. Background:.
Saunders Lin, MD, MPA +2 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Frontiers in Forests and Global Change, 2023 Brown spot needle blight (BSNB), caused by Lecanosticta acicola (Thüm.) Syd., is an emerging forest disease of Pinus species originating from North America and introduced to Europe and Asia.
Nikica Ogris +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source