Results 31 to 40 of about 346 (113)
Across 47 Phase 3 trials in Crohn's disease and ulcerative colitis, placebo exposure was associated with measurable harm. Disease exacerbation events showed the greatest excess risk, with one additional exacerbation occurring for every 8–13 patients assigned to placebo rather than active therapy.
Joëlle St‐Pierre +5 more
wiley +1 more source
This study examines the reuse readiness of photovoltaic modules through the Swiss PV Circle project. Results confirm technical feasibility with cost savings from targeted preselection, whereas economic viability depends on module age, testing, and market conditions.
Roger Nyffenegger +6 more
wiley +1 more source
QUEST: Quasar unsupervised encoder and synthesis tool
Context. Quasars at the redshift frontier ( z > 7.0) are fundamental probes of black hole growth and evolution, but are notoriously difficult to identify. At these redshifts, machine-learning-based selection methods have proven to be efficient, but require appropriate ...
F. Guarneri +7 more
openaire +2 more sources
Direct Ink Writing of Geopolymer Composites Reinforced With Polypropylene Fibers
ABSTRACT Polypropylene fiber (PPf) reinforced geopolymer inks were systematically optimized for extrusion‐based additive manufacturing through regulation of ink composition, rheological parameters, nozzle size, and fiber content. The effects of polyethylene glycol (PEG) content and H2O to K2O ratio on printability were investigated.
Chuhui Qin, Paolo Colombo
wiley +1 more source
Abstract Background Magnetic resonance imaging (MRI) for radiation therapy treatment planning is currently being used in many anatomical sites to better visualize soft tissue landmarks, a technique known as an MRI simulation. A core component of modern MRI simulation configurations are the use of external laser positioning systems (ELPS) to help set up
Lucas McCullum +3 more
wiley +1 more source
The general relativistic theory of quasars
The paper was a preliminary and rejected by the author attempt to describe compact relativistic objects.
openaire +2 more sources
Dark energy is the largest fraction of the energy density of our universe — yet it remains one of the enduring enigmas of our times. Here we show that dark energy can be used to solve 2 tantalizing mysteries of the observable universe. We build on existing models of dark energy linked to neutrino masses.
openaire +2 more sources
Plasmonic Enhancement of Fluorescence and Protein Dynamics in Living Mammalian Cells
This study demonstrates plasmonic enhancement of the function of fluorescent voltage sensing proteins (genetically encoded voltage indicators, (GEVIs), QuasAr6) in live mammalian cells. Coupling to plasmonic nanoparticles does not just increase fluorescence, but influences the protein photocycle, creating a hybrid sensor with its response speed to ...
Marco Locarno +16 more
wiley +1 more source
UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro +7 more
wiley +1 more source
Optimizing over Multiple Distributions under Generalized Quasar-Convexity Condition
We study a typical optimization model where the optimization variable is composed of multiple probability distributions. Though the model appears frequently in practice, such as for policy problems, it lacks specific analysis in the general setting.
Shihong Ding +3 more
openaire +3 more sources

