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A Quasi-Species Model for the Propagation and Containment of Polymorphic Worms

IEEE Transactions on Computers, 2009
Polymorphic computer worms are characterized by their ability to change their byte sequence as they replicate and propagate, thereby aiming to thwart intrusion detection systems (IDSes). In this letter, we propose a model based on coevolution of biological quasi-species to characterize the propagation of polymorphic worms and the effect of IDSes on ...
B. Stephenson, B. Sikdar
semanticscholar   +3 more sources

Dynamics of quasi-species models with a complex spin coherent state representation

Journal of the Korean Physical Society, 2012
We investigate the dynamics of the parallel mutation-selection quasi-species model of biological evolution for various fitness landscapes. By using the semiclassical propagator for spin coherent states, for the linear fitness landscape, we find the expression for the transition rate from an arbitrary initial state to an arbitrary final state and ...
M. Ancliff, Jeong-Man Park
semanticscholar   +3 more sources

Effect of epistasis on the evolution of the quasi-species model

Journal of the Korean Physical Society, 2012
Epistasis is a phenomenon of non-additive interactions between genes in determining phenotypes. We investigate how epistasis affects the evolution of the quasi-species model by using the parallel mutation-selection (ParaMuSe) quasi-species evolution model.
Jeong-Man Park, Yung-Gyung Kang
openaire   +2 more sources

Helicobacter pylori: molecular evolution of a bacterial quasi-species

Current Opinion in Microbiology, 1998
Helicobacter pylori persists chronically within individuals and as they spread the mutating bacteria migrate with them. The continuous selection and microevolution generates a population of closely related but different bacteria that behave like a quasi-species. Within this heterogeneity, H.
Antonello Covacci, Rino Rappuoli
openaire   +3 more sources

A Binary Solution Strategy Enables High-Efficiency Quasi-2D Perovskite Solar Cells with Excellent Thermal Stability.

ACS Nano, 2023
Quasi-two-dimensional (2D) perovskites are highly promising light-harvesting materials for commercialization of perovskite solar cells (PSCs) owing to the excellent materials stability.
Tong Yue   +19 more
semanticscholar   +1 more source

Genetic variation and quasi-species

Current Opinion in Genetics & Development, 1992
During the past year the relative fitness, that is, overall replication ability, and the fitness gain of animal virus variants have been quantified, providing new insight into the dynamics for the generation of RNA virus quasi-species. Measurements of mutant frequencies and rates of genetic diversification have confirmed the extreme complexity of RNA ...
openaire   +3 more sources

Survival Probability of Quasi-Species under Environmental Changes

Journal of the Korean Physical Society, 2008
We investigate the evolution of biological organisms under changing environments by using a Monte Carlo simulation of the parallel mutation-selection model for quasi-species, as well as a mean-eld analysis. For a given severity (how large the change is) and frequency (how often the change occurs) of the environmental change, biological organisms evolve
Jeong-Man Park, Yung-Gyung Kang
openaire   +2 more sources

A Quasi-Species Approach for Modeling the Dynamics of Polymorphic Worms

Proceedings IEEE INFOCOM 2006. 25TH IEEE International Conference on Computer Communications, 2006
Polymorphic worms can change their byte sequence as they replicate and propagate, thwarting the traditional signature analysis techniques used by many intrusion detection systems (IDSes). As the incidence of such worms becomes more frequent, it is important to understand their behavior and interaction with the IDSes in order to develop effective ...
B. Sikdar, B. Stephenson
openaire   +2 more sources

Emergence of Novel Enzyme Quasi-Species Depends on the Substrate Matrix

Journal of Molecular Biology, 2008
Current research on enzyme evolution has shown that many enzymes are promiscuous and have activities with alternative substrates. Mutagenesis tends to relax substrate selectivity, and evolving enzymes can be regarded (summed over evolutionary time) as clusters of enzyme variants, or "quasi-species," tested against a "substrate matrix" defined by all ...
Abeer Shokeer   +2 more
openaire   +3 more sources

Multi-substrate-activity space and quasi-species in enzyme evolution: Ohno's dilemma, promiscuity and functional orthogonality.

Biochemical Society Transactions, 2009
A functional enzyme displays activity with at least one substrate and can be represented by a vector in substrate-activity space. Many enzymes, including GSTs (glutathione transferases), are promiscuous in the sense that they act on alternative ...
B. Mannervik   +2 more
semanticscholar   +1 more source

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