Environmental differences explain subtle yet detectable genetic structure in a widespread pollinator
Background The environment is a strong driver of genetic structure in many natural populations, yet often neglected in population genetic studies.
Marcel Glück +2 more
doaj +1 more source
Functionally diverging molecular quasi-species evolve by crossing two enzymes [PDF]
Molecular evolution is frequently portrayed by structural relationships, but delineation of separate functional species is more elusive. We have generated enzyme variants by stochastic recombinations of DNA encoding two homologous detoxication enzymes, human glutathione transferases M1–1 and M2–2, and explored their catalytic versatilities.
Lars O. Emrén +4 more
openalex +3 more sources
We report the nucleotide sequences of three citrus viroids belonging to three different genera: Citrus exocortis viroid (CEVd), Hop stunt viroid (HSVd) and Citrus viroid-III (CVd-III) isolated from a single natural infected Citrus reticulata var ...
Amine Elleuch +6 more
doaj +1 more source
Digital evolution in time-dependent fitness landscapes [PDF]
We study the response of populations of digital organisms that adapt to a time-varying (periodic) fitness landscape of two oscillating peaks. We corroborate in general predictions from quasi-species theory in dynamic landscapes, such as adaptation to the
Li, Ye, Wilke, Claus O.
core +1 more source
Quasi-species evolution maximizes genotypic reproductive value (not fitness or flatness) [PDF]
AbstractGrowing efforts to measure fitness landscapes in molecular and microbial systems are motivated by a longstanding goal to predict future evolutionary trajectories. Sometimes under-appreciated, however, is that the fitness landscape and its topography do not by themselves determine the direction of evolution: under sufficiently high mutation ...
openaire +4 more sources
APOBEC3 Interference during Replication of Viral Genomes
Co-evolution of viruses and their hosts has reached a fragile and dynamic equilibrium that allows viral persistence, replication and transmission. In response, infected hosts have developed strategies of defense that counteract the deleterious effects of
Luc Willems, Nicolas Albert Gillet
doaj +1 more source
Indoor/outdoor relationships and mass closure of quasi-ultrafine, accumulation and coarse particles in Barcelona schools [PDF]
The mass concentration, chemical composition and sources of quasi-ultrafine (quasi-UFP, PM0.25), accumulation (PM0.25–2.5) and coarse mode (PM2.5–10) particles were determined in indoor and outdoor air at 39 schools in Barcelona (Spain ...
M. Viana +7 more
doaj +1 more source
Huge Progeny Production during the Transient of a Quasispecies Model of Viral Infection, Reproduction and Mutation [PDF]
Eigen's quasi-species model describes viruses as ensembles of different mutants of a high fitness "master" genotype. Mutants are assumed to have lower fitness than the master type, yet they coexist with it forming the quasi-species.
Cuesta, José A.
core +3 more sources
Oseltamivir-Resistant Influenza A Pandemic (H1N1) 2009 Virus, Hong Kong, China
Resistance to oseltamivir was observed in influenza A pandemic (H1N1) 2009 virus isolated from an untreated person in Hong Kong, China. Investigations showed a resistant virus with the neuraminidase (NA) 274Y genotype in quasi-species from a ...
Honglin Chen +7 more
doaj +1 more source
Viroids: sequence variability and evolution of pathogenic RNA
Viroids as the smallest pathogenic circular single-stranded pathogenic RNAs form populations of quasi-species, whichhas been recently identified by thermodynamic methods like TGGE pre-selection and heteroduplex analysis.
J. Matoušek
doaj +1 more source

