Results 111 to 120 of about 325,836 (358)
Cognitive and Patient‐Reported Outcome Measures in LGI‐1‐IgG Autoimmune Encephalitis
ABSTRACT Objective Clinical outcome measures for autoimmune encephalitis (AE) are not yet well defined. Cognitive outcome measures (CogOs) and patient‐reported outcomes (PROs) may capture the symptoms of AE, beyond clinician‐reported outcomes (ClinROs) (the Modified Rankin Scale [mRS] and Clinical Assessment Scale in Autoimmune Encephalitis [CASE ...
Tatchaporn Ongphichetmetha+8 more
wiley +1 more source
After a short-lived »ban«, the Quaternary has again been formalized as a chronostratigraphic unit, consisting of the Pleistocene and the Holocene. The exact base and the GSSP (Global Boundary Stratotype Section and Point) are yet to be formally recognized by the IUGS (International Union of Geological Sciences), however it is expected that the ...
openaire +3 more sources
ABSTRACT Objective The cervical spinal cord (cSC) is highly relevant to clinical dysfunction in multiple sclerosis (MS) but remains understudied using quantitative magnetic resonance imaging (MRI). We assessed magnetization transfer ratio (MTR), a semi‐quantitative MRI measure sensitive to MS‐related tissue microstructural changes, in the cSC and its ...
Lisa Eunyoung Lee+26 more
wiley +1 more source
In the following memoir I propose to make an attempt at an enumeration of the invariants, covariants, and contravariants of a quaternary cubic, that is to say, of a homogeneous function of the third order in four variables, which geometrically represents a Surface of the third order.
openaire +2 more sources
Further Hominid Remains of Lower Quaternary Age from the Chou Kou Tien Deposit [PDF]
Davidson Black
openalex +1 more source
ABSTRACT Objective The Apolipoprotein (APOE) ε4 allele is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD); however, many ε4 carriers remain cognitively intact into old age. Leveraging plasma neuron‐derived extracellular vesicles (NDEVs), we sought to identify biomarkers of cognitive resilience and their interplay with APOE ...
Apostolos Manolopoulos+17 more
wiley +1 more source
Repeat Expansions in PLIN4 Cause Autosomal Dominant Vacuolar Myopathy With Sarcolemmal Features
ABSTRACT Objective We aim to describe and characterize two unrelated Spanish families suffering from an autosomal dominant autophagic vacuolar myopathy caused by repeat expansions in PLIN4. Methods We evaluated the clinical phenotype and muscle imaging, and performed a genetic workup that included exome sequencing, muscle RNAseq, and long‐read genome ...
Laura Llansó+17 more
wiley +1 more source
Sedimentology of Modern Bahamian Carbonate Slopes: Summary and Update
Slopes adjacent to the Bahamian carbonate platform revealed a large variety of depositional processes. In this study, we present a synthesis summarizing 109,000 km2 of bathymetric and reflectivity data with ∼7,900 km of seismic lines and 311 m of ...
K. Fauquembergue+10 more
doaj +1 more source
ABSTRACT Objective Prognostication of disease course and prediction of treatment response in multiple sclerosis is an unmet need. We compared the performance of serum neurofilament light chain Z scores (age‐ and BMI‐adjusted) with absolute concentrations for the prediction of response to disease‐modifying therapy.
Maximilian Einsiedler+43 more
wiley +1 more source
Tertiary and Post-Tertiary Changes of the Atlantic and Pacific Coasts. With a note on The Mutual Relations of Land-Elevation and Ice-Accumulation during the Quaternary Period [PDF]
Joseph Le Conte
openalex +1 more source