Landscape of BRAF transcript variants in human cancer
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda+5 more
wiley +1 more source
Generalized q-Method Relative Pose Estimation for UAVs with Onboard Sensor Measurements. [PDF]
Stanfield K, Bani Younes A, Hayajneh M.
europepmc +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
Identification of Defects in Low-Speed and Heavy-Load Mechanical Systems Using Multi-Fusion Analytic Mode Decomposition Method. [PDF]
Liu Y, Zhang K, Yang M, Zhang X, Xu Y.
europepmc +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
Complete solid-body rotation rate measurements of micro-plastic curved fibers in turbulence. [PDF]
Caridi GCA+3 more
europepmc +1 more source
Intrinsic Functions on Matrices of Real Quaternions [PDF]
C. G. Cullen
openalex +1 more source
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
A dual-stream model based on PRNU and quaternion RGB for detecting fake faces. [PDF]
Hua M, Li S, Wang J.
europepmc +1 more source
Classification of $SO(n)$ -bundles over the quaternion projective plane [PDF]
Seiya Sasao, Itiro Tamura
openalex +1 more source