Discussion: “Principles of a General Quaternion-Operator Method of Spatial Kinematic Synthesis” (Sandor, George N., 1968, ASME J. Appl. Mech., 35, pp. 40–46) [PDF]
E. J. F. Primrose
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Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho+11 more
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A novel approach for three-dimensional evaluation of reduction morphology in distal radius fracture. [PDF]
Yoshii Y+6 more
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Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
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A Novel Loosely Coupled Collaborative Localization Method Utilizing Integrated IMU-Aided Cameras for Multiple Autonomous Robots. [PDF]
Liu C, Wang T, Li Z, Li S, Tian P.
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On a certain change of affine connections on an almost quaternion manifold [PDF]
Shigeyoshi Fujimura
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This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
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Two Methods for Superposing the Structures of Like-Molecule Assemblies: Application to Peptide and Protein Oligomers and Aggregates. [PDF]
Liwo A, Leśniewski M.
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Quadratic forms over nonformally real fields with a finite number of quaternion algebras [PDF]
Craig M. Cordes
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
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