Enhancing the security of horizontal canal BPPV repositioning maneuvers: insights from virtual simulation. [PDF]
Li J, Hu H, Zhang Y, Yang X.
europepmc +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
In-Motion Alignment with MEMS-IMU Using Multilocal Linearization Detection. [PDF]
Zhong Y, Chen X, Gao N, Jiao Z.
europepmc +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Identification of Defects in Low-Speed and Heavy-Load Mechanical Systems Using Multi-Fusion Analytic Mode Decomposition Method. [PDF]
Liu Y, Zhang K, Yang M, Zhang X, Xu Y.
europepmc +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
A dual-stream model based on PRNU and quaternion RGB for detecting fake faces. [PDF]
Hua M, Li S, Wang J.
europepmc +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Color Normalization in Breast Cancer Immunohistochemistry Images Based on Sparse Stain Separation and Self-Sparse Fuzzy Clustering. [PDF]
Traisuwan A +4 more
europepmc +1 more source

