Results 281 to 290 of about 56,344 (329)

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

CONSTRUCTION OF CONFIDENCE REGIONS FOR UNCERTAIN SPATIAL DISPLACEMENTS WITH DUAL RODRIGUES PARAMETERS. [PDF]

Proc ASME Des Eng Tech Conf
Yu Z, Jeffrey Ge Q, Langer MP.
europepmc   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Phase transitions in the rolling of irregular cylinders and spheres. [PDF]

Proc Natl Acad Sci U S A
Qian D, Jung Y, Mahadevan L.
europepmc   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Global attractive set for quaternion-valued neural networks with neutral items. [PDF]

Sci Rep
Wu X, Tu Z, Peng T, Wang D.
europepmc   +1 more source

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

FEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang, Yuan Cao, Jing Du, Ying Zhang, Junxia Wang, Ying Yuan, Lianqing Sun   +6 more
wiley   +1 more source

Constructing Kinematic Confidence Regions With Double Quaternions. [PDF]

Proc MSR RomanSy 2024 (2024)
Ge QJ, Yu Z, Purwar A, Langer MP.
europepmc   +1 more source

Design and dynamics analysis of three-degree-of-freedom kinematic mechanism for helicopter attitude simulation. [PDF]

Sci Rep
Liu T, Ding J, Xu J, Zhao D, Qiu X.
europepmc   +1 more source

A novel Gaussian sum quaternion constrained cubature Kalman filter algorithm for GNSS/SINS integrated attitude determination and positioning system. [PDF]

Front Neurorobot
Dai Q, Xiao GR, Zhou GH, Ye QQ, Han SY.
europepmc   +1 more source