Results 131 to 140 of about 120,004 (268)

Evolución de componentes de computación cuántica y mediciones cuánticas no destructivas en la informática moderna

open access: yesCiencia UNEMI, 2018
El presente trabajo, realiza una breve introducción a las medidas QND (Quantum nondemolition measurement) y sus características. Además, se describe teóricamente un qubit acoplado a un oscilador armónico cuántico forzado como ejemplo de una medición QND
Cristian Espinel López   +3 more
doaj  

ELF5‐Mediated Enhancer–Promoter Interaction Regulates LALBA Expression in Ovine Mammary Gland

open access: yesAdvanced Science, EarlyView.
In the study, we systematically investigate the epigenetic mechanisms underlying lactation traits in sheep by integrating transcriptomic, chromatin accessibility, histone modification, and functional analyses. We identify a super‐enhancer at the LALBA locus and demonstrate that enhancer E4 functions as its core regulatory element.
Xinmiao Wu   +11 more
wiley   +1 more source

A Living Multi‐Omics PDX Biobank of High‐Risk Sarcomas Reveals ecDNA‐Driven Oncogene Amplification in Osteosarcoma and Enables Preclinical Precision Oncology

open access: yesAdvanced Science, EarlyView.
A living multi‐omics sarcoma PDX biobank is enriched for high‐risk disease and preserves key patient tumor features at histopathological and molecular levels. Integrated profiling reveals ecDNA‐driven oncogene amplification in osteosarcoma and preferential retention of ecDNA during PDX evolution.
Weisong Zhao   +34 more
wiley   +1 more source

Structural Variants in the Human Genome Associated With Gut Microbiome and Blood Metabolic Traits With Potential Causal Links

open access: yesAdvanced Science, EarlyView.
Based on a multi‐omics cohort of 2002 individuals comprising high‐depth whole‐genome and metagenomic sequencing data, blood metabolites, and detailed questionnaires, we identified 138 859 high‐confidence SVs, uncovering 36 significant SV–microbiome associations and 48 SV–blood metabolite associations.
Qun Zhou   +13 more
wiley   +1 more source

Ultrafast single-qubit gates through multi-photon transition removal. [PDF]

open access: yesNat Commun
Gao Y   +14 more
europepmc   +1 more source

Optical Access to Dark Excitons Via Spin–Phonon Fano Interference

open access: yesAdvanced Science, EarlyView.
Dark excitons in quantum dots neither absorb nor emit light and stay hidden from optical spectroscopy. Quantum interference now reveals them: light scattered by acoustic phonons interferes with a phonon‐assisted spin flip between bright and dark exciton, carving a Fano dip into the spectrum whose position gives the bright–dark splitting. Magnetic field,
Janina J. Schindler   +7 more
wiley   +1 more source

Tumor‐Intrinsic HEXB Drives Endothelial‐To‐Mesenchymal Transition and Confers Resistance to Anti‐Angiogenic Therapy in Glioblastoma

open access: yesAdvanced Science, EarlyView.
This study elucidates how glioblastoma tumors develop resistance to anti‐VEGF therapy through endothelial‐to‐mesenchymal transition (Endo‐MT). The researchers identify a novel signaling pathway where tumor‐derived HEXB stabilizes HSP60 to drive this vascular reprogramming.
Tianqi Liu   +13 more
wiley   +1 more source

Multi‐Omics Analyses Identify Candidate Genes Associated With Stage‐Specific Quality Formation in Mulching‐Treated Moso Bamboo Shoots

open access: yesAdvanced Science, EarlyView.
Organic mulching reprograms Moso bamboo shoot development, enhancing yield and nutritional quality. This multi‐omics study reveals that coordinated metabolic, transcriptional, and post‐transcriptional regulation drives stage‐specific quality formation, offering comprehensive insights into how this agricultural practice improves crop performance and ...
Bo Wang   +7 more
wiley   +1 more source

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