Results 181 to 190 of about 248,456 (339)

Dissecting the Spatial and Single‐Cell Transcriptomic Architecture of Cancer Stem Cell Niche Driving Tumor Progression in Gastric Cancer

Advanced Science, EarlyView.
A single‐cell and spatial transcriptional atlas reveals the architecture of human gastric cancer stem cell (CSC) niche and the developmental trajectory of CSCs. These CSCs interact with immunosuppressive immune cells thereby constructing immune‐suppressive niche, and inflammatory cancer‐associated fibroblast (iCAFs) to enhance stemness through ...
Guangyu Zhang, Xin Zhang, Wenting Pan, Xizhao Chen, Lingfei Wan, Chunjie Liu, Yuting Yong, Yue Zhao, Shuli Sang, Lihua Zhang, Sheng Yao, Yushu Guo, Mingmei Wang, Xinhui Wang, Guangdun Peng, Xinlong Yan, Yanchun Wang, Min Zhang   +17 more
wiley   +1 more source

Multi‐omics analyses reveal the interaction between colonic microbiota and host in Min and Yorkshire pigs

Animal Research and One Health, EarlyView., 2023
In the present study, we created the weight gain models with Min and Yorkshire pigs and conducted the metagenomics and metabolomics of colon contents and transcriptomics of colon tissue. Further, we revealed the characteristics and functions of the colonic microbiota in Min and Yorkshire pigs and analyzed their interactions with the host. Overall, this
Xiaoyu Huang, Huihui Li, Feng Cheng, Ligang Wang, Guoqing Cao, Lixian Wang, Lijun Shi   +6 more
wiley   +1 more source

Revealing the Origin and Nature of the Buried Metal‐Substrate Interface Layer in Ta/Sapphire Superconducting Films

Advanced Science, EarlyView.
The origin and nature of metal‐substrate interface layer in Ta/sapphire‐based superconducting films is investigated using synchrotron X‐ray reflectivity and scanning transmission electron microscopy. An intermixing layer, ≈0.65 nm thick containing Al, O, and Ta atoms, is identified at the interface.
Aswin k. Anbalagan, Rebecca Cummings, Chenyu Zhou, Junsik Mun, Vesna Stanic, Jean Jordan‐Sweet, Juntao Yao, Kim Kisslinger, Conan Weiland, Dmytro Nykypanchuk, Steven L. Hulbert, Qiang Li, Yimei Zhu, Mingzhao Liu, Peter V. Sushko, Andrew L. Walter, Andi M. Barbour   +16 more
wiley   +1 more source

<title>Multilevel quantum particle as a few virtual qubits materialization</title> [PDF]

, 2000
A. R. Kessel, Vladimir L. Ermakov
openalex   +1 more source

A Compound Screen Based on Isogenic hESC‐Derived β Cell Reveals an Inhibitor Targeting ZnT8‐Mediated Zinc Transportation to Protect Pancreatic β Cell from Stress‐Induced Cell Death

Advanced Science, EarlyView.
Pancreatic β cell loss by cellular stress contributes to diabetes pathogenesis. The study demonstrates that WFS1–ZnT8–zinc axis regulates vicious cycle of zinc transportation and cellular stress in pancreatic β cell. Based on that, the study applies a strategy for compound screening targeting ZnT8 based on human models, and identifies anisomycin, as a ...
Rui Hu, Qing Ma, Yunhui Kong, Zhaoyue Wang, Minglu Xu, Xiangyi Chen, Yajuan Su, Tinghui Xiao, Qing He, Xuan Wang, Wenjun Xu, Yiling Yang, Xushu Wang, Xiaobo Li, Yanfang Liu, Shuangshuang Chen, Rui Zhao, Meng Guo, Gaowei Wang, Weida Li   +19 more
wiley   +1 more source

Anything but qubits

, 2013
Poster presented at the Photons Beyond Qubits workshop in Olomouc, April 2013. Three topics are briefly covered: * Cat state amplification by conditional homodyning * Displacement-enhanced entanglement distillation * Towards an efficient single photon source with NV centres in an open microcavity The first two are theoretical schemes for quantum ...
Neergaard-Nielsen, Jonas, Laghaout, Amine, Ioannes Rigas, Kragh, Christian, Ros, Elisa Da, Hansen, Jacob Kjærsgaard, Andersen, Ulrik Lund   +6 more
openaire   +2 more sources

Monolithic 3D Oscillatory Ising Machine Using Reconfigurable FeFET Routing for Large‐Scalability and Low‐Power Consumption

Advanced Science, EarlyView.
This paper introduces a novel M3D Oscillatory Ising Machine (OIM) utilizing FeFETs as in‐memory routing switches and biristors as oscillators. The system achieves precise control, scalability, and low power consumption, solving complex optimization problems like MaxCUT problem.
Joon Pyo Kim, Song‐Hyeon Kuk, Hyun Wook Kim, Jaeyong Jeong, Juhyuk Park, Bong Ho Kim, Jongmin Kim, Aida Todri‐Sanial, Sanghyeon Kim   +8 more
wiley   +1 more source

Decoherence Control for Optical Qubits

, 1998
David Vitali, Paolo Tombesi
openalex   +2 more sources

Citrullination of NF‐κB p65 by PAD2 as a Novel Therapeutic Target for Modulating Macrophage Polarization in Acute Lung Injury

Advanced Science, EarlyView.
Peptidyl arginine deiminase 2 (PAD2) plays a key role in regulating macrophage function in Pseudomonas aeruginosa‐induced acute lung injury (ALI). Using single‐cell RNA sequencing and proteomics, a new PAD2‐catalyzed citrullination site on NF‐κB p65 (171 Arginine), modulating macrophage polarization is identified.
Xin Yu, Yujing Song, Tao Dong, Wenlu Ouyang, Chao Quan, Liujiazi Shao, Leonard Barasa, Paul R. Thompson, Mao Zhang, Jianjie Ma, Katsuo Kurabayashi, Yongqing Li   +11 more
wiley   +1 more source

The Type III Secretion System (T3SS) of Escherichia Coli Promotes Atherosclerosis in Type 2 Diabetes Mellitus

Advanced Science, EarlyView.
Large‐scale studies indicate a strong relationship between the gut microbiome, type 2 diabetes mellitus (T2DM), and atherosclerotic cardiovascular disease (ASCVD). Here, a higher abundance of the type III secretion system (T3SS) virulence factors of Enterobacteriaceae/Escherichia‐Shigella in patients with T2DM‐related‐ASCVD, which correlates with their
Yao‐Yuan Zhang, Song‐Tao Chen, Gang Chen, Le Zhou, Guo‐Liang Zhou, Xin‐Yuan Yu, Long Yuan, Wei‐Qian Deng, Zhen‐Bo Wang, Jing Li, Yi‐Fu Tu, Da‐Wei Zhang, Yuan li, Abdul Sammad, Xiao Zhu, Kai Yin   +15 more
wiley   +1 more source