Results 261 to 270 of about 251,773 (344)

A Resource-Virtualized and Hardware-Aware Quantum Compilation Framework for Real Quantum Computing Processors. [PDF]

open access: yesResearch (Wash D C)
Xu HZ   +13 more
europepmc   +1 more source

Targeting G3BP1 Condensate Topology Promotes Stress Granule Assembly via m6A‐IGF2BP1 for Ischemic Stroke Rescue

open access: yesAdvanced Science, EarlyView.
Our research reveals that small‐molecule icariin (ICA) directly binds Ras‐GTPase‐activating protein SH3 domain‐binding protein 1 (G3BP1), inducing conformational change and oligomerization. This interaction confers neuroprotection by recruiting insulin‐like growth factor 2 mRNA‐binding protein 1 (IGF2BP1) and modulating N6‐methyladenosine (m6A ...
Ling Li   +17 more
wiley   +1 more source

Simulating the quantum switch with quantum circuits is computationally hard. [PDF]

open access: yesNat Commun
Bavaresco J   +6 more
europepmc   +1 more source

Stromal Cell‐Mast Cell Communication Orchestrates Anti‐Viral Immunity in the Meninges

open access: yesAdvanced Science, EarlyView.
This study delineates the spatial distribution and postnatal maturation of meningeal mast cells and uncovers their essential role in antiviral immunity. Using genetic models, mast cells are shown to promote CD8⁺ T cell infiltration and viral clearance via IL‐33 receptor signaling and synergistic activation by IL‐33 and ATP from infected stromal cells ...
Qingqing Li   +7 more
wiley   +1 more source

Atomically Resolved Electron Reflectivity at a Metal/Semiconductor Interface

open access: yesAdvanced Science, EarlyView.
An atomically flat interface is achieved in the incoherent Al/Ge heterostructure using molecular beam epitaxy (MBE). Scanning tunneling microscopy (STM) reveals a laterally periodic modulation of electron reflectivity with atomic resolution at the commensurate Al/Ge interfacial lattice, originating from the local electronic states.
Ding‐Ming Huang   +5 more
wiley   +1 more source

Error mitigation with stabilized noise in superconducting quantum processors. [PDF]

open access: yesNat Commun
Kim Y   +12 more
europepmc   +1 more source

12‐HETE Is an Endogenous Modulator of BLT2 Triggering Vascular Degeneration, Dissection, and Rupture

open access: yesAdvanced Science, EarlyView.
In thoracic aortic dissection (TAD), elevated levels of the arachidonic acid metabolite 12‐HETE, produced by macrophage‐specific 12/15‐lipoxygenase (12/15‐LOX), bind to the BLT2 receptor on vascular cells. This activates the NOX‐1/ROS/NF‐κB signaling pathway, leading to IL‐6 release.
Yuyu Li   +13 more
wiley   +1 more source

High‐Resolution Multiplexed Sequencing of Single‐Cell Full‐length Transcriptome Via Combinational Barcoded Tn5 Transposon Insertion

open access: yesAdvanced Science, EarlyView.
CBTi‐seq is reported, leveraging Tn5 transposase‐mediated molecular assembly of combinatorial barcodes and UMIs for high‐resolution multiplexed sequencing of the full‐length transcriptome in single cells. This approach achieves molecular resolution by end‐to‐end sequencing, enabling reconstruction of splice variants and accurate quantification of ...
Liyong He   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy