Results 271 to 280 of about 251,773 (344)

SLPI⁺ AT2‐Like Cells Orchestrate Lung Adenocarcinoma Invasion via Wnt Pathway Activation and Stromal Crosstalk in a Spatially Defined Margin Niche

open access: yesAdvanced Science, EarlyView.
Integrating spatial transcriptomics and single‐cell RNA sequencing, this study identifies a novel subpopulation of SLPI⁺ AT2‐like cells at the invasive margin of lung adenocarcinoma (LUAD). These cells, through stromal crosstalk and Wnt pathway activation, promote tumor stemness and invasion.
Zhoufeng Wang   +13 more
wiley   +1 more source

Alternative Pathway for Methyl Supply through the Coupling of SHMT1 and PEMT to Maintain Astrocytic Homeostasis in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.
Yue‐Han Chen   +17 more
wiley   +1 more source

A Perspective on Interactive Theorem Provers in Physics

open access: yesAdvanced Science, EarlyView.
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley   +1 more source

Constructing Qubit Edge States by Inverse-Designing the Electromagnetic Environment. [PDF]

open access: yesACS Photonics
Miguel-Torcal A   +4 more
europepmc   +1 more source

High‐Rate Cross‐Channel Entanglement Swapping Between Independent On‐Chip Sources

open access: yesAdvanced Science, EarlyView.
To interconnect individual chip‐based quantum sources, high‐performance entanglement swapping is indispensable. Here, using low‐loss silicon chips with waveguide structure and frequency‐offset pumps, this work demonstrates high‐rate cross‐channel entanglement swapping.
Haoyang Wang   +5 more
wiley   +1 more source

The phase diagram of quantum chromodynamics in one dimension on a quantum computer. [PDF]

open access: yesNat Commun
Than AT   +10 more
europepmc   +1 more source

Scrambling‐Enhanced Quantum Battery Charging in Black Hole Analogues

open access: yesAdvanced Science, EarlyView.
By employing a black‐hole‐analog quantum battery constructed from a position‐dependent XY model, its dynamical behavior is investigated through a quench of the scrambling parameter. It is systematically quantified that how the simulated scrambling improves key performance metrics‐namely, stored energy, peak power, and charging time‐thereby offering a ...
Zhilong Liu   +3 more
wiley   +1 more source

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