Results 281 to 290 of about 180,551 (346)

Use of LC‐MS to characterize host cell protein removal during depth filtration

open access: yesBiotechnology Progress, EarlyView.
Abstract The removal of host cell proteins (HCPs) is crucial in biopharmaceutical production, as residual impurities can impact product safety and efficacy. While a number of studies have demonstrated that depth filtration can provide significant HCP removal, there is little information on its effectiveness in removing specific HCPs.
Liang‐Kai Chu   +3 more
wiley   +1 more source

Benchmarking Quantum Gates and Circuits. [PDF]

open access: yesChem Rev
Tripathi V   +5 more
europepmc   +1 more source

First‐line serplulimab plus chemotherapy in extensive‐stage small‐cell lung cancer: Updated results and biomarker analysis from the ASTRUM‐005 randomized clinical trial

open access: yesCancer Communications, EarlyView.
Abstract Background The ASTRUM‐005 study previously demonstrated a significant overall survival (OS) benefit with serplulimab (a programmed death 1 inhibitor) plus chemotherapy versus chemotherapy alone in previously untreated extensive‐stage small‐cell lung cancer (ES‐SCLC).
Ying Cheng   +32 more
wiley   +1 more source

Simvastatin overcomes the pPCK1‐pLDHA‐SPRINGlac axis‐mediated ferroptosis and chemo‐immunotherapy resistance in AKT‐hyperactivated intrahepatic cholangiocarcinoma

open access: yesCancer Communications, EarlyView.
Abstract Background Intrahepatic cholangiocarcinoma (ICC) is a challenging cancer with an increasing incidence. The Phase III TOPAZ‐1/KEYNOTE‐966 study demonstrated chemo‐immunotherapy (CIT) as a significant advancement, potentially replacing traditional chemotherapy for advanced biliary tract cancer.
Jinghan Zhu   +12 more
wiley   +1 more source

The Electronic Spin State of Diradicals Obtained from the Nuclear Perspective: The Strange Case of Chichibabin Radicals

open access: yesChemPhysChem, Volume 26, Issue 6, March 15, 2025.
The electronic spin state of two Chichibabin radicals is investigated using 2‐dimensional hyperfine correlated Electron Nuclear Double Resonance. The protons (I=1/2) act as a reference for the electronic spin quantum number (S) via their hyperfine interactions.
Gabriel Moise   +7 more
wiley   +1 more source

Integrated photonic source of Gottesman-Kitaev-Preskill qubits. [PDF]

open access: yesNature
Larsen MV   +35 more
europepmc   +1 more source

Micro‐size aperture surface acoustic wave generator for cell lysis

open access: yesDroplet, EarlyView.
Micro‐size aperture interdigitated transducer for cell lysis of cell inside droplets. Abstract The breakage of the cellular membrane for releasing intracellular material is the starting point for several diagnostics or treatment processes. Surface acoustic waves can provide a novel and chemical‐free approach by inducing acoustic streaming generating ...
Gonzalo Almanza   +6 more
wiley   +1 more source

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