Results 341 to 350 of about 311,633 (389)

Hybrid classical and quantum computing for enhanced glioma tumor classification using TCGA data. [PDF]

Sci Rep
Akpinar E, Oduncuoglu M.
europepmc   +1 more source

Cryogenic Neuromorphic Synaptic Behavior in 180 nm Silicon Transistors for Emerging Computing Systems

Advanced Intelligent Systems, EarlyView.
This study investigates the neuromorphic plasticity behavior of 180 nm bulk complementary metal oxide semiconductor (CMOS) transistors at cryogenic temperatures. The observed hysteresis data reveal a signature of synaptic behavior in CMOS transistors at 4 K.
Fiheon Imroze, Bhavani Yalagala, Naveen Kumar, Mostafa Elsayed, Meraj Ahmad, Robert Graham, Vihar Georgiev, Hadi Heidari, Martin Weides   +8 more
wiley   +1 more source

Spin-qubit control with a milli-kelvin CMOS chip. [PDF]

Nature
Bartee SK, Gilbert W, Zuo K, Das K, Tanttu T, Yang CH, Dumoulin Stuyck N, Pauka SJ, Su RY, Lim WH, Serrano S, Escott CC, Hudson FE, Itoh KM, Laucht A, Dzurak AS, Reilly DJ.   +16 more
europepmc   +1 more source

Identification of a Second‐Hit Brain Somatic DEPDC5 Variant Supports Causality of a DEPDC5 Germline Variant of Uncertain Significance. Time for a Classification Update?

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Germline variants in DEPDC5 are a cause of familial focal epilepsy with variable foci. Affected individuals may have focal cortical dysplasia if a second brain somatic variant occurs. As access to brain tissue is limited, the second somatic hit in the brain is usually presumed if a clear pathogenic germline variant is present. Here, we present
Ala'a Alsayed, Zainab Hakim, Daria Merrikh, Maryam Khanbabaei, Navprabhjot Kaur, Walter Hader, Tyler Soule, Setareh Ashtiani, Grace Polanco‐Tovar, Morris Scantlebury, Hamed Rahi, Yang Cao, Jennifer A. Chan, Juan P. Appendino, Gerald Pfeffer, Ping Yee Billie Au, Karl Martin Klein   +16 more
wiley   +1 more source

Accurate quantum-centric simulations of intermolecular interactions. [PDF]

Commun Phys
Kaliakin D, Shajan A, Liang F, Robledo Moreno J, Li Z, Mitra A, Motta M, Johnson C, Saki AA, Das S, Sitdikov I, Mezzacapo A, Merz KM.   +12 more
europepmc   +1 more source

Novel Intragenic Duplication of GATAD2B in a Patient With GAND

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The nucleosome remodeling and deacetylation (NuRD) complex is a major chromatin regulator and plays a critical role in regulating gene transcription, genome integrity, and cell cycle progression. Heterozygous variants in GATAD2B, a core NuRD component, have been reported to cause GATAD2B‐Associated Neurodevelopmental Disorder (GAND), an ...
Mari Mori, Steven Estes, Swetha Ramadesikan, Betsy Schmalz, Shayne Plourde, Maria E. Hernandez Gonzalez, Anthony R. Miller, Bimal P. Chaudhari, Richard K. Wilson, Daniel C. Koboldt   +9 more
wiley   +1 more source

Tensor-based quantum phase difference estimation for large-scale demonstration. [PDF]

Proc Natl Acad Sci U S A
Kanno S, Sugisaki K, Nakamura H, Yamauchi H, Sakuma R, Kobayashi T, Gao Q, Yamamoto N.   +7 more
europepmc   +1 more source

Treg Cells Modulate Neuroinflammation and Behavioral Deficits in Autism: Evidence From MR‐Based Genetic Analyses and Experimental Models

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental condition that is increasingly linked to immune dysfunction and neuroinflammation. Regulatory T cells (Tregs), which are crucial in maintaining immune homeostasis, have been implicated in the pathogenesis of ASD.
Zuqing Nie, Xinyi Xu, Junhao Chen, Huiling Chen, Meng Li, Yang Zhang, Zhiwei Li, Chen Shen, Jie Wen, Xia Cao   +9 more
wiley   +1 more source

Baseband control of single-electron silicon spin qubits in two dimensions. [PDF]

Nat Commun
Unseld FK, Undseth B, Raymenants E, Matsumoto Y, de Snoo SL, Karwal S, Pietx-Casas O, Ivlev AS, Meyer M, Sammak A, Veldhorst M, Scappucci G, Vandersypen LMK.   +12 more
europepmc   +1 more source