Results 31 to 40 of about 619,141 (335)
Molecular effect of an OPTN common variant associated to Paget's disease of bone [PDF]
, 2018 Paget's disease of bone (PDB) is a chronic bone disorder and although genetic factors appear to play an important role in its pathogenesis, to date PDB causing mutations were identified only in the Sequestosome 1 (SQSTM1) gene at the PDB3 locus.
Brown, Jacques P. +5 more
core +3 more sources
The Alien \u3ci\u3eHippodamia Variegata\u3c/i\u3e (Coleoptera: Coccinellidae) Quickly Establishes Itself Throughout Wisconsin [PDF]
, 2018 (excerpt) Hippodamia variegata (Goeze) (Coleoptera: Coccinellidae) is a Palaearctic species that was first reported to be established in the Nearctic near Montreal, Quebec, in 1984 (Gordon 1987). Since then, this small beetle has been expanding its range
Williams, Andrew H, Young, Daniel K
core +2 more sources
Carabid Beetles (Coleoptera: Carabidae) as Prey of North American Frogs [PDF]
, 2017 In this paper, 62 species of carabid beetles are listed as prey of frogs. Records are from the literature and a stomach contents study. During the period May to October 1973, I collected and examined the stomach contents of 2 bullfrogs, 45 green frogs ...
Larochelle, Andre
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan +5 more
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Manipulating time-bin qubits with fiber optics components [PDF]
, 2006 We propose two experimental schemes to implement arbitrary unitary single qubit operations on single photons encoded in time-bin qubits. Both schemes require fiber optics components that are available with current technology.Comment: 2 pages, 3 figures ...
Berlin, Guido +4 more
core +2 more sources
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
What are Canadian Labor Laws as They Relate to Leave Administration, Specifically Military, Disability, FMLA, Vacation and Bereavement? [PDF]
, 2013 Question: What are Canadian labor laws as they relate to leave administration, specifically military, disability, FMLA, vacation and bereavement?
Calder, Jane, Macfarlane, Bryan
core +1 more source
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas +18 more
wiley +1 more source