Results 211 to 220 of about 79,436 (293)

RETRACTED: Polygenic risk score and prostate specific antigen predict death from prostate cancer in men with intermediate aggressive cancer

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Using 21 SNPs, two novel PRS were constructed and used to develop two new machine‐learning classifiers, one for the detection of prostate cancer and the other for the prediction of its aggressiveness and subsequent mortality. The classifier for disease detection is built using the PRS as the sole feature, whereas the one for disease ...
Leandro Rodrigues Santiago   +3 more
wiley   +1 more source

Age at First Pregnancy, Adult Weight Gain and Postmenopausal Breast Cancer Risk: The PROCAS Study (United Kingdom)

open access: yesInternational Journal of Cancer, EarlyView.
An early first pregnancy is protective against postmenopausal breast cancer. However, pregnancy is also a key contributor to weight gain, and adult weight gain increases postmenopausal breast cancer risk. This prospective cohort study quantified the combined effect of adult weight gain and age at first pregnancy on postmenopausal breast cancer risk ...
Lee Malcomson   +7 more
wiley   +1 more source

Improving asthma case detection among children and adolescents through clinic-based screening in primary care health facilities in Uganda: a cluster randomised trial. [PDF]

open access: yesBMJ Open Respir Res
Nantanda R   +7 more
europepmc   +1 more source

Evaluating the Impact of Age on Prostate Cancer Overdiagnosis Using Long‐Term Follow‐Up From the CAP Randomised Trial

open access: yesInternational Journal of Cancer, EarlyView.
Uncertainty persists over whether the benefits of prostate‐specific antigen (PSA) screening outweigh harms from overdiagnosis, a key barrier to population‐wide adoption. Here, English male mortality rates were analyzed alongside long‐term data from the UK Cluster Randomized Trial of PSA Testing for Prostate Cancer (CAP) to estimate age‐specific ...
Adam R. Brentnall   +5 more
wiley   +1 more source

Leading across boundaries: establishment of the UCLH community outreach intrathecal baclofen refill service. [PDF]

open access: yesBMJ Open Qual
Keenan E   +7 more
europepmc   +1 more source

Lymphocyte Micronucleus Formation Is Driven by Inflammation‐Induced Oxidative DNA Damage in Oesophageal Cancer Development

open access: yesInternational Journal of Cancer, EarlyView.
Chromosomal instability is a hallmark of cancer, but minimally invasive ways to detect systemic DNA damage and cancer risk remain limited. Here, using patient blood samples, the authors investigated lymphocyte micronuclei (MN) frequency as a potential marker of DNA damage across the progression from gastroesophageal reflux disease to Barrett's ...
Kathryn Munn   +13 more
wiley   +1 more source

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