Results 111 to 120 of about 51,917 (261)
Expanding the electroclinical spectrum of TANC2‐related disorders: Lennox–Gastaut syndrome and related developmental epileptic phenotypes
Epilepsia Open, EarlyView.Abstract Objective
Neurodevelopmental disorders (NDDs) and epilepsy are often associated. Increasing evidence highlights a pivotal role for pathogenic variants in genes encoding synaptic scaffolding proteins. Within this group, TANC2 has recently been implicated in intellectual developmental disorder with autistic features and language delay, with or ...Lorenzo Perilli, Carlotta Stipa, Gianmichele Villano, Laura Licchetta, Leo Strothmann, Robin Tobias Jauss, Gerhard Josef Kluger, Raffaella Minardi, NETRE consortium, Giuseppe Gobbi, Salvatore Grosso, Francesca Bisulli, Pasquale Striano +12 morewiley +1 more sourceLong‐Term Trends and Projections of the Global Epilepsy Burden: Insights From the Global Burden of Disease Study 2021
Health Care Science, EarlyView.Targeted interventions addressing socioeconomic inequalities and health service disparities are essential for mitigating future epilepsy burdens, especially in low‐resource settings. ABSTRACT Background
Epilepsy is a common neurological disorder imposing significant global health burdens. A comprehensive understanding of its temporal and spatial trends Du Cai, Xianze Li, Qiwen Yuan, Zhongming Lian, Chenyu Zhao, Baotian Zhao, Xiu Wang, Chao Zhang, Lin Sang, Wenhan Hu, Xiaoqiu Shao, Jianguo Zhang, Shichuo Li, Jiajie Mo, Kai Zhang +14 morewiley +1 more sourceHealth System Factors in Head and Neck Cancer Diagnosis: A HEADSpAcE Consortium Qualitative Study in Glasgow and Montevideo
Head &Neck, EarlyView.ABSTRACT Background
Head and neck cancer (HNC) is a devastating diagnosis, with advanced‐stage disease leading to poorer outcomes. This qualitative study aimed to identify health system factors associated with stage of HNC diagnosis. Methods
Qualitative semistructured interviews with HNC patients and clinicians were undertaken in two purposively ...Grant Creaney, Iván Lyra González, Mauricio Cuello, Mariél de Aquino Goulart, Alex D. McMahon, Claire Paterson, James McCaul, Maja Popovic, Lorenzo Richiardi, Silvia Lopez de Blanc, Maria Paula Curado, Marta Vilensky, HEADSpAcE Consortium, Elmira Ebrahimi, Apiwat Sangphukieo, Hanla A Park, Valerie Gaborieau, Wolfgang Ahrens, Laia Alemany, Lidia MRB Arantes, Jaroslav Betka, Cristina Canova, David I Conway, Mauricio Cuello, Maria Paula Curado, Ana Carolina de Carvalho, Jose Carlos de Oliviera, Mark Gormley, Maryam Hadji, Claire M Healy, Ivana Holcatova, Luis P Kowalski, Pagona Lagiou, Areti Lagiou, Gary J Macfarlane, Sandra Perdomo, Luis Felipe Ribiero Pinto, Jose Roberto V Podesta, Jerry Polesel, Miranda Pring, Hamideh Rashidian, Ricardo R Gama, Lorenzo Richiardi, Max Robinson, Paula A Rodriguez‐Urrego, Sheila C Soares‐Lima, Nicolas Timpson, Marta Vilensky, Sandra V von Zeidler, Tim Waterboer, Kazem Zendehdel, Ariana Znaor, Paul Brennan, James McKay, Shama Virani, Tom Dudding, Roque Adam, Antonio Agudo, Shaymaa F AlWaheidi, Miquel Angel Pavon, Namrah Anwar, Paola Engelmann Arantes, Lisa Arguello, Yubelly Avello, Lucas Avondet, Ana M Baldión‐Elorza, Camila Batista Daniel, Bianca Beraldi, Barbara Berenstein, Patricia Bernal, Natália Bernardino Rodrigues, Josipa Bilic Zimmermann, Marianna G Botta, Jesús Brenes, Nicole Brenner, Carol Brentisci, Catalina Burtica, María L Cabañas, Erick Cantor, Raiany S Carvalho, Andre L Carvalho, Luigi Chiusa, Priscilia Chopard, Qurratulain Chundriger, Omar Clavero, Isabela Costa, Grant Creaney, Cecilia Cuffini, Tauana C Dias, Evandro Duccini de Souza, Lais C Durant, Alberto Escallón, Gisele Aparecida Fernandes, Béatrice Fervers, Valentina Fiano, Frederico Firme Figueira, Regina Furbino Villefort, Manuela Gangemi, Paolo Garzino‐Demo, Mahin Gholipour, Raul Giglio, Mariel A Goulart, Jéssica Graça Sant'Anna, Marek Grega, Anna Clara Gregório Có, Arnau Guasch, Jose A Hakim, David N Hayes, Marco Homero de Sá Santos, Katrina Hurley, Magalí Insfran, Giuseppe C Iorio, Moghira Iqbaluddin Siddiqui, Jannik Johannsen, Martin Kaňa, Jens Peter Klussmann, Evelio Legal, Jeferson Lenzi, Fernando Luiz Dias, Iván Lyra González, Willene Machado Zorzaneli, Ricardo Mai Rocha, Manel Mañós, Priscila Marinho de Abreu, Maryam Marzban, James McCaul, Alex D. McMahon, Carlos Mena, Elismauro F Mendonça, Laura Mendoza, Lorena Meza, Birgitta Michels, Matinair S Mineiro, Chiara Moccia, Pamela Mongelos, Ana L Montealegre‐Páez, Francisca Morey Cortes, Alvaro Muñoz, Andy Ness, Aline B Neves, Marco Oliva, José Carlos de Oliveira, Hernán Ortiz, José Ortiz, Marta Osorio, Vanessa Ospina, Oliviero Ostellino, Mauricio Palau, Claire Paterson, Sonia Paytubi Casabona, Giancarlo Pecorari, David M Pereira, Olivia Pérol, Shahid Pervez, Alicia Pomata, Maja Popovic, Alisson Poveda, Carol P Prado, Kristina M Prager, Guglielmo Ramieri, Juliana NI Rego, Rui M Reis, Helene Renard, Umberto Ricardi, Giuseppe Riva, Frederic Rodilla, Ingrid Rodriguez, María I Rodríguez, Alastair Ross, Pierre‐Eric Roux, Tazeen Saeed Ali, Pierre Saintigny, Juan J Santivañez, Cristóvam Scapultampo‐Neto, Javier Segovia, Agenor Sena, Ricardo Serrano, Shachi J Sharma, Oliver Siefer, Stephanie Smart, Bruna P Sorroche, Cinthia Sosa, Juliana Souza de Oliveira, Antonella Stura, Steven Thomas, Oscar Torres, Sara Tous, Gonzálo Ucross, Adriana Valenzuela, José Roberto Vasconcelos de Podestá, Alex Whitmarsh, Sylvia Wright, Shaymaa Alwaheidi, Paul Brennan, Shama Virani, Al Ross, David I Conway +196 morewiley +1 more sourceAdverse Health Events in Chronic Myeloid Leukaemia Patients Treated With Tyrosine Kinase Inhibitors 2009–2019: A Real‐World Study From the UK's Haematological Malignancy Research Network
International Journal of Cancer, EarlyView.Although tyrosine kinase inhibitors (TKIs) improve chronic myeloid leukemia (CML) outcome, long‐term effects remain unclear, particularly in real‐world settings. Here, the authors examined morbidity and mortality in CML patients treated with TKIs between 2009 and 2019 in the United Kingdom.Eleanor Kane, Alexandra Smith, Debra Howell, Catherine Cargo, Kate Rothwell, Simone Green, Russell Patmore, Eve Roman +7 morewiley +1 more sourceBrexit and Its Impact on EU Financial Markets
International Journal of Finance &Economics, EarlyView.ABSTRACT
We investigate the impact of Brexit on volatility spillovers across the EU countries. We introduce a Brexit intensity measure that assigns an intensity score reflective of the financial markets' reaction to the events that occurred as Brexit negotiations began to unfold.Marwan Izzeldin, Gulnur Muradoglu, Vasileios Pappas, Sheeja Sivaprasad +3 morewiley +1 more sourceIntegrative host–microbiome modeling uncovers the implication of oral–gut translocation in advanced cirrhosis
iMeta, EarlyView.Liver cirrhosis is associated with profound disruption of host–microbiome metabolic interactions. Using paired oral and fecal metagenomics combined with genome‐scale metabolic modeling, we investigated how microbial translocation along the oral–gut axis influences microbial metabolism at different cirrhosis severities.Yi Jin, Frederick Clasen, Fernando Garcia‐Guevara, Sania Arif, Robert Schierwagen, Gholamreza Bidkhori, Michael Praktiknjo, Maximilian J. Brol, Frank E. Uschner, Florence A. Castelli, Nicolas Pons, Benoit Quinquis, Nathalie Galleron, Kevin Da Silva, Christophe Junot, Debbie L. Shawcross, David L. Moyes, Rajiv Jalan, S. Dusko Ehrlich, Vishal C. Patel, Jonel Trebicka, Saeed Shoaie +21 morewiley +1 more source
