Results 31 to 40 of about 130,649 (354)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Judging a Book by its Cover: Examining Reader Reception of Peritexts in Queer Young Adult Literature

open access: yesInternational Journal of Young Adult Literature, 2023
The rise of LGBTQIA+ and queer young adult (YA) literature has led to an increased diversity in the range of texts available for young readers. The covers of these texts use various design elements to market to their target audiences, employing ...
Annika Herb, David Betts
doaj   +1 more source

Exploring the Q in LGBTQ: Demographic characteristic and sexuality of Queer people in a U.S. representative sample of sexual minorities.

open access: yesPsychology of Sexual Orientation and Gender Diversity, 2020
Although queer identity has been used among sexual minorities for decades, little is known about the population of queer-identified people in the U.S. We compared people who identify as queer (unweighted n = 88; weighted % = 5.8%) with those who identify
Shoshana K. Goldberg   +3 more
semanticscholar   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Tradition and gender

open access: yesNordisk Tidskrift för Socioonomastik
Until recently, little attention has been given to men’s surname choices in couples. By analysing men’s narratives, this study investigates the motivations and social implications of their choices.
Line Førre Grønstad
doaj   +1 more source

European Code Against Cancer, 5th edition – hormone replacement therapy, other common medical therapies and cancer

open access: yesMolecular Oncology, EarlyView.
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat   +18 more
wiley   +1 more source

4/ Queering death in the medical and health humanities

open access: yesWhatever, 2021
This is part 4 of 6 of the dossier What do we talk about when we talk about queer death?, edited by M. Petricola. The contributions collected in this article sit at the crossroads between thanatology, queer studies, and the medical/health humanities and ...
Yana Kirey-Sitnikova   +4 more
doaj   +1 more source

Unapologetic: A Black, Queer, and Feminist Mandate for Radical Movements

open access: yesJournal of Critical Thought and Praxis, 2019
This is an overview and honest review of the 192 page, paperback edition of Unapologetic: A Black, Queer, and Feminist Mandate for Radical Movements, authored by Charlene Carruthers.

semanticscholar   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Building a model of navigational strategies for queer undergraduate students in STEM

open access: yesFrontiers in Sociology, 2023
IntroductionThere is a critical need to foster inclusive educational spaces for Queer identifying students and to resist oppressive structures that seek to marginalize and inflict trauma on students because of their gender or sexual identity ...
Matthew Voigt   +6 more
doaj   +1 more source

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