We delineate a TGFβ1/SMAD/lnc‐APUE/E‐cadherin axis wherein TGFβ1 signaling activates lnc‐APUE; lnc‐APUE subsequently downregulates E‐cadherin expression via Alu element‐driven STAU1‐mediated decay of CDH1 mRNA, thereby promoting tumor metastasis. Our findings reveal a novel regulatory function for lnc‐APUE within the SMD pathway, elucidate a distinct ...
Song‐Yang Li +10 more
wiley +1 more source
VOCs Profiling and Quality Assessment of Milk Employing Odorant-Binding Proteins-Based Fluorescence Biosensor. [PDF]
Giannattasio C +3 more
europepmc +1 more source
This study shows that amyloid fibrils form nematic condensates via liquid–liquid crystalline phase separation (LLCPS). With increasing pH, this transition shifts toward disordered condensates formed through liquid–liquid phase separation (LLPS), in which birefringence with lack of a coherent nematic field symmetry originates from enthalpic fibril ...
Milad Radiom, Raffaele Mezzenga
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Bioenergy Cropping Reduces the Spatiotemporal Scaling of Soil Bacterial Biodiversity
Consistent with patterns observed in plant and animal communities, soil bacterial communities exhibit significant species–time–area and phylogenetic–time–area relationships independent of nested structure. Bioenergy cropping significantly reduces the spatiotemporal scaling rates, particularly in sandy loam soils.
Zhencheng Ye +19 more
wiley +1 more source
A practical guide to long-term field PAM chlorophyll fluorescence measurements: setup, installation, data processing with R package 'LongTermPAM' and interpretation. [PDF]
Zhang C +7 more
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RIPK3 Orchestrates Scar‐Associated Macrophage Dysfunction to Drive Pulmonary Fibrosis
Beyond signaling cell death, RIPK3 emerges as a critical metabolic regulator in pulmonary fibrosis. This research reveals that RIPK3 promotes PI3K‐AKT signaling in scar‐associated macrophages to fuel polyamine synthesis, independent of its kinase activity.
Tao Yang +12 more
wiley +1 more source
Liquid Crystal Monomers (LCMs) of Emerging Concern: Recent Progress and Challenges in Wastewater Treatment. [PDF]
Mohapatra S +4 more
europepmc +1 more source
Gleeble-Simulated Ultra-Fast Cooling Unlocks Strength-Ductility Synergy in Fully Martensitic Ti-6Al-4V. [PDF]
Xiao Y, Zhou H, Liu P, Chen L.
europepmc +1 more source
Resolving the "Thick-Wall Challenge" in Haematococcus pluvialis: From Metabolic Reprogramming to Clinical Translation. [PDF]
Chen T, Zhu X, Liao Q.
europepmc +1 more source
Regulation of Light Absorption and Energy Dissipation in Sweet Sorghum Under Climate-Relevant CO<sub>2</sub> and Temperature Conditions. [PDF]
Li JJ, Liu LH, Ye ZP, Zhang CW, Yang XL.
europepmc +1 more source

