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Relaxant and antioxidant capacity of red wine polyphenols on isolated mice corpora cavernosa [PDF]

open access: yes, 2014
Boydens, Charlotte   +4 more
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The quercetin paradox

Toxicology and Applied Pharmacology, 2007
Free radical scavenging antioxidants, such as quercetin, are chemically converted into oxidation products when they protect against free radicals. The main oxidation product of quercetin, however, displays a high reactivity towards thiols, which can lead to the loss of protein function.
Rodger Duffin   +6 more
openaire   +3 more sources

Mechanism of antioxidant properties of quercetin and quercetin-DNA complex

Journal of Molecular Modeling, 2020
Quercetin is the most abundant flavonoid with potent antioxidant activities. In the current research, the antioxidant properties of quercetin and quercetin-DNA complex were investigated theoretically and experimentally. Free radical scavenging experiments with thiobarbituric acid-reactive substances (TBARS) and 1,1-diphenyl-2-trinitrophenylhydrazine ...
Liguo Gao, Xiaoli Song, Yali Wang
openaire   +3 more sources

Quercetin

2016
Quercetin is a natural flavonoid found abundantly in vegetables and fruits. There is growing evidence suggesting that quercetin has therapeutic potential for the prevention and treatment of different diseases, including cardiovascular disease, cancer, and neurodegenerative disease.
Anumantha G. Kanthasamy   +5 more
openaire   +2 more sources

Quercetin and the mutagenicity of wines

Mutagenesis, 1993
Various studies have shown the mutagenicity of red wine. The major mutagens identified in red wine have been flavonoids, i.e. rutin and its aglycone quercetin. Besides flavonoids, however, it has recently been reported that H2O2 may account for the mutagenicity of red wine in the L-Arabinose resistance test.
J, Gaspar   +5 more
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Quercetin pharmacokinetics in humans

Biopharmaceutics & Drug Disposition, 2008
AbstractThe purpose of this study was to examine the pharmacokinetics of quercetin aglycone as well as its conjugated metabolites and to develop a population pharmacokinetic model for quercetin that incorporates enterohepatic recirculation. The stability of quercetin in different matrices at various temperatures and pH, and the quercetin content of six
Liang Wang   +3 more
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The Preparation and Analysis of Quercetin

Journal of the American Pharmaceutical Association (Scientific ed.), 1953
Quercetin (3, 3′, 4′, 5, 7-pentahydroxyflavone ) was prepared by hydrolysis with dilute acids of the naturally occurring glycosides, rutin and quercitrin. Data were ogtained on the rate of hydrolysis of pure glycosides in concentrations from 2 to 10%.
Charles F. Krewson, J. Naghski
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Inactivation of quercetin mutagenicity

Food and Chemical Toxicology, 1984
Combinations of oxygen and alkaline pH were found to inactivate irreversibly the mutagenicity of quercetin towards Salmonella typhimurium strain TA98. Exposure time, quercetin concentration and polyphenol oxidase were also important variables determining the extent of quercetin inactivation.
Mendel Friedman, G. A. Smith
openaire   +3 more sources

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